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Pharmacology Soup for the Dental Hygiene Soul. Paragon Hygiene Academy November 14 & 15 2013 Ted A. Beitelschees, DDS. Pharmacology Soup for the Dental Hygiene Soul. Goals Consider some clinically significant adverse rxns to the Top 50 drugs
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Pharmacology Soup for the Dental Hygiene Soul Paragon Hygiene Academy November 14 & 15 2013 Ted A. Beitelschees, DDS
Pharmacology Soup for the Dental Hygiene Soul Goals • Consider some clinically significant adverse rxns to the Top 50 drugs • Discuss some pharm “wrinkles” to selected dental drugs • Look at some emerging trends in perio/oral health care and how they relate to pharmacology • Give you tools for next week!
Pharmacology Soup for the Dental Hygiene Soul Review the Top 50 Drugs
Top 50 Drugs Breakdown • 10 Cardiac Drugs • 5 Statins 4 Pain Control 5 Antibiotics 5 Respiratory Drugs 5 Sedative/Hyp
Top 50 Drug Review - adverse reactions Xerostomia Orthostatic Hypotension Polypharmia Gingival Enlargement (Hyperplasia)
Selected alcohol-free products • Biotene • Oxyfresh products • Listerine Zero & Total Care Zero • Butler GUM chlorhexidine gluconate 0.12% rinse
Flouride • Treatment – varnish, rinse, gel, toothpaste, tray • Restorative materials – bonding agents, composites, glass ionomer cements
Sodium Laurel Sulfate (SLS)–free toothpastes • Arm & Hammer Advance White for SensitiveTeeth • Burt's Bees Natural Toothpaste • Biotene Sensitive • Sensodyne - Original, Iso-Active, ProNamel, Extra Whitening, Cool Gel, Fresh Impact, Tartar Control plus Whitening, Fresh Mint • Tom's of Maine Peppermint SLS-free Anticavity Plus Whitening Clean and Gentle
Drugs that can cause Ginvigal Enlargement (Hyperplasia) • phenytoin (Dilantin) • nifedipine (Procardia, Adalat) • diltiazem (Cardizem) • verapimil (Calan) • amlodipine (Norvasc)
Local Anesthetics Tricks with CVD Patients • Use 1:200,000 epi LA • Mix plain LA with LA & vaso • Still must watch total dosage!
Local Anesthetics Infiltration of mandibular molars with 4% articane (Septocaine) w/ 1:100,000 or 1:200,000 epi • 75% success on 1st molars • 50% success on 2nd molars
Refractory Perio Aces Metronidazole (Flagyl) • Great against anaerobes • Gets into GCF • Watch alcohol
Refractory Perio Aces Doxycycline hyclate (Vibramycin) • Dosed once daily • 4x concentration in GCF ! • Watch sun worshippers
First-Line Antihypertensives hydrochlorothiazide (HCTZ, Diazide) metaprolol (Tenormin) ACE Inhibitors • captopril (Capoten) and enalpril (Vasotec)
Trouble on the HTN front reserpine (Serpasil) guanethidine (Ismelin) Other centrally acting (CNS) drugs Multiple drugs
Reducing Vascular Inflammation • Statins • e.g. rosuvastatin (Crestor) • ACE inhibitors • e.g. ramipril (Altace)
Future Trends Perio Therapy will be considered Preventive Care
Pharmacology Soup for the Dental Hygiene Soul Thank You ! Ted Beitelschees, DDS drted@WestgateFamilyDental.com 419.578.4100
Pharmacology Soup for the Dental Hygiene Soul Questions ?