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Comparative Effectiveness Research Data Infrastructure Resource: Pharmetrics LifeLink

Bradley C. Martin, PharmD, PhD. Comparative Effectiveness Research Data Infrastructure Resource: Pharmetrics LifeLink. Pharmetrics LifeLink™ . De-identified commercial paid claims data 98 Health Plans 61 million unique patients 16 million covered lives per year

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Comparative Effectiveness Research Data Infrastructure Resource: Pharmetrics LifeLink

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  1. Bradley C. Martin, PharmD, PhD Comparative Effectiveness ResearchData Infrastructure Resource:Pharmetrics LifeLink

  2. Pharmetrics LifeLink™ • De-identified commercial paid claims data • 98 Health Plans • 61 million unique patients • 16 million covered lives per year • Claims and Membership spanning 1997 – 2011 • Average member enrollment duration of two and a half years

  3. Diagnoses ICD9-CM Diagnosis codes Co-morbidities Adverse events Up to four diagnosis per record Date of diagnosis Patient Demographics and Eligibility Age Gender Region Product and Payer Type Enrollment Begin and End Dates Medical Services Hospitalizations ER visits Office visits Home care Diagnostic tests Procedures Injections Health Plan ClaimsPatient Information

  4. Regional Distribution of Enrollees in LifeLink Midwest 7.7M (26.7M) East5.9M (14.1M) West4.8M (10.0M) South4.6M (18.9M)

  5. Distribution of Enrollees Compared to U.S. Census by Age/Sex

  6. Patient Counts For Selected Diagnoses

  7. IMS Pharmetrics LifeLink™ TRI - Files • 10% Random Sample • Annual SAS Files 1997 -2011 • Sorted by encrypted enrollment ID and Date of Service • Separated Medical Claims from Pharmacy Claims • Developed unique file structure for pharmacy and medical claims • Merged key fields from NDC file to pharmacy claims • Constructed Proxy Pharmacy Benefit Eligibility Indicator • Further Adjudicated Duplicate and Overlapping Rx Claims • Building in some disease classification systems

  8. Concordance Possible Under Treatment Percentage Concordance with Model Warfarin Recommended (Grade I) Model Rcmndtn (Warfarin) %Concordance Model Rcmndtn (Warfarin) %Concordance Model Rcmndtn (Warfarin) %Concordance 2,429 47.18% 301 40.53% 731 38.99% 7,259 51.18% 157 40.13% 68 47.06% 1,273 58.76% 0 - 0 -

  9. Access • No Charge to Access Data • Free UAMS TRI CER Technical Assistance • Free Access to Data Documentation • Low Administrative Burden to Access Data • Streamlined Data Use Agreement • Local access on UAMS server

  10. Contact Information • Bradley C. Martin, Pharm.D., Ph.D. Phone: (501) 603.1992Email: bmartin@uams.edu • Mick Tilford, Ph.D. Phone (501) 526-6642 Email: TilfordMickJ@uams.edu

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