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SIAM III Trial. Randomized trial of thrombolysis (rPA) with transfer for early PCI (within 6 hours; n=82) or thrombolysis with delayed angiography at 2 weeks (n=81) in patients with acute MI presenting at community hospitals. Death/reMI/ischemic events/TLR at 6 months p=0.001. EF at 6 months
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SIAM III Trial Randomized trial of thrombolysis (rPA) with transfer for early PCI (within 6 hours; n=82) or thrombolysis with delayed angiography at 2 weeks (n=81) in patients with acute MI presenting at community hospitals Death/reMI/ischemic events/TLR at 6 months p=0.001 EF at 6 months p=0.018 rPA + Delayed PCI rPA + Delayed PCI rPA + Early PCI rPA + Early PCI J Am Coll Cardiol 2003;42:634-41