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LIPID ANABOLISM. acetyl-CoA carboxylase. fig 21-1. acetyl-CoA carboxylase. fig 21-1. acetyl-CoA carboxylase. fig 21-1. condensation. fig 21-2. reduction. fig 21-2. dehydration. fig 21-2. reduction. fig 21-2. synthesis of fatty acids…. fig 21-4. synthesis of fatty acids….
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LIPID ANABOLISM
acetyl-CoA carboxylase fig 21-1
acetyl-CoA carboxylase fig 21-1
acetyl-CoA carboxylase fig 21-1
condensation fig 21-2
reduction fig 21-2
dehydration fig 21-2
reduction fig 21-2
synthesis of fatty acids… fig 21-4
synthesis of fatty acids… fig 21-4
acyl carrier protein (ACP) in E. coli a lot like… fig 21-4
coenzyme A fig 16-3
AcCoA-ACP transacetylase (AT) fig 21-6 (4th)
malonyl-CoA- ACP transferase (MT) fig 21-6 (4th)
b-ketoacyl-ACP synthase (KS) fig 21-6
b-ketoacyl-ACP reductase (KR) fig 21-6
b-hydroxyacyl-ACP dehydratase (HD) fig 21-6
enoyl-ACP reductase (ER) fig 21-6
acetylCoA-ACP transacetylase (AT) fig 21-6
fatty acid synthases variations of the FAS complex fig 21-7
two sources of NADPH… fig 21-9
citrate as a source of building blocks… fig 21-10
and a minor NADPH source… majority supplied by pentose phosphate p.way fig 21-10
Phosphorylation of fatty acid synthesis active un-phosphorylated ACC makes cytosolic filaments fig 21-11
now what…? elongation desaturation fig 21-12
provided by plants: polyunsat. fatty acids fig 21-14.
cyclooxygenase a key reaction of inflammation in mammals… fig 21-15.
willow bark aspirin: a cycloxygenase inhibitor fig 21-15.
a family of COX inhibitors: NSAIDs box 21-2
a family of COX inhibitors: NSAIDs box 21-2
Two COX isozymes COX1 gastric functions COX2 inflammation pain fever box 21-2
COX2-specific inhibitors box 21-2
lipid menagerie phospholipid triglyceride
phospholipids or glycerophospholipids phophatidylcholine phophatidylserine
mobilizing glycerol fig 21-17.
adding acyl groups phosphatidic acid a phospholipid fig 21-17.
more phospholipids or glycerides… fig 21-18.
anatomy of a phospholipid fig 21-23.
another trinucleotide- based carrier: CTP
The isoprene unit: a branched lipid structure
four stages of cholesterol synthesis fig 21-33