1 / 9

Tobacco Mosaic Virus (TMV)

Tobacco Mosaic Virus (TMV). Presentation by Tristan Vranizan. History. TMV: the first virus to be discovered Late 19th Century: Researchers found out that a tiny infectious agent was the cause of a disease that was killing tobacco plants.

ziazan
Download Presentation

Tobacco Mosaic Virus (TMV)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tobacco Mosaic Virus (TMV) Presentation by Tristan Vranizan

  2. History • TMV: the first virus to be discovered • Late 19th Century: Researchers found out that a tiny infectious agent was the cause of a disease that was killing tobacco plants. • Wendell Stanley coaxed the virus to form crystals and found out that it was mainly composed of proteins. • RNA (Ribonucleic acid) was also discovered in the virus Wendell Stanley >> Won Nobel prize for his study.

  3. Description of Molecule • TMV has one strand of RNA, shown in red. • RNA is wrapped with stacks of protein, shown in blue. • Protein Coat: 2,130 copies of a small protein stack on top of each other, spiraling downward. • RNA strand is encoded in four proteins, transporting the RNA from cell to cell and allowing the virus to spread.

  4. Infection • TMV is so stable it can survive in cigars for years made from infected tobacco leaves. • The coat of proteins, around the RNA strand, protect it from any enzymes trying to kill it. • But, in order for TMV to spread it has to release it’s coat of proteins for the RNA to enter a cell • The proteins, situated outside the cell, repel against each other. This allows the cell to release RNA back into the coat of proteins to spread again. Healthy tobacco leaf > < TMV infected leaf

  5. Assembly • Mixing RNA with capsid proteins creates a functional virus. • Two steps create this process • Step 1: Proteins form into a two-layer disk, RNA then fills the hole at the center causing the proteins to form into a ring, eventually covering the RNA. • Step 2: RNA is ensured to being packaged into viruses with its’ need for an initiation sequence.

  6. Structure • 17 subunits surround the RNA in red. • RNA is located in the grooves of the protein, wedged between them. • 3 nucleotides bind each protein subunit.

  7. Structure (continued) • The bright red dots are the acidic amino acids. • They help to break up the virus inside infected cells.

  8. Other plants with TMV

  9. Picture References • http://erec.ifas.ufl.edu/tomato-scouting-guide/images/diseases/tobacco-mosaic135.JPG • http://erec.ifas.ufl.edu/tomato-scouting-guide/diseases/tobacco-mosaic-virus.shtml • http://matyasciprian.hu/kepek/paprika_betegsegek/paprika_tmv_3.JPG

More Related