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Endobronchial Therapy : Stents and Stunts. Prof Mordechai Kramer Rabin Medical Center Petach-Tikva Israel. at RMC Bronchoscpies. Endoscopic paliation. Relief of Airway obstruction: Laser Brachytherapy Stenting Single Multiple Balloon dilatation Closure of fistula.
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Endobronchial Therapy: Stents and Stunts Prof Mordechai Kramer Rabin Medical Center Petach-Tikva Israel
Endoscopic paliation • Relief of Airway obstruction: • Laser • Brachytherapy • Stenting • Single • Multiple • Balloon dilatation • Closure of fistula
Brachytherapy • 1921-Yankaur Radon 222 seeds • 1961-Pool Ra 222- • 1965- Johnston, Gibbons Au 198 • 1979- Mittal -Brachytherapy with FOB • 1984-Percarpio - Ir 192 afterloading
Brachytherapy-Technique • Outpatient basis • Short, mild sedation • HDR delivery system • Two/Three sessions 7-14 days apart • 500-750 Rads (1500-2250 total)
Indications • Malignant • Primary lung malignancy • Secondary metastasis • Benign • Granulation tissue • Stents • Transplantation
Brachytherapy-Indications • Trachea and major airways • Endobronchial involvement • Can be added to laser/stents/balloon dilatation • Can be added to external beam radiation and chemotherapy
Brachytherapy Vs. Laser therapy • Brachytherapy • Slow action • Deeper and wider action • Requires lumen for catheter • Short procedure • Laser • Rapid action • Superficial action • Creates lumen • Bleeding control • Sometimes prolonged procedure
Brachytherapy-Results • Complete airway opening-42% • Partial opening- 36% • Failure- 22% • Significant palliation • Effect on survival??
Brachytherapy is an easy, safe and effective modality for palliation of malignant airway obstruction • Brachytherapy can be added to either local and/or systemic modalities • Brachytherapy may have some effect on survival • Brachytherapy can be used safely in non-malignant condition, albeit longer follow up is needed Conclusions
- אמת או שקר Laser Vs Stent • LASER is an acronym for light amplification by stimulated emission of radiation • Stents were invented in 1856 by the English dentist Charles Stent (1807–1885) • לייזר פיירמן המציא את שיטת הלייזר בשנת 1960 • שיטת הסטנט הוכנסה לשימוש עי John Holder בשנת 1988
Airway Stenting- Indications • Malignant • Bronchogenic carcinoma • Metastatic tumor • Direct invasion- Thyroid, Esophageal etc • Compression of airways by nearby tumor
Stent types • Metal • Silicon
Stenting is a viable option in malignant stenosis Technically, stenting is easy to perform with experienced team Combination therapy with laser and radiotherapy is commonly used Summary
The goal is to prevent and relieve suffering and to improve quality of life for people facing serious, complex illness. Palliation