Indiana CTSI HUB Update

1. Indiana CTSI HUB Update www.indianactsi.org Bill Barnett Director, Information Infrastructures, Indiana CTSI iCTSI Program Directors Meeting February 23, 2010

2. Summary • Goals of this Presentation • What is the Indiana CTSI HUB? • HUB Accomplishments • Current HUB-based Initiatives • How Can the HUB Help Your Program? www.indianactsi.org

3. Goals • You understand what the HUB is, its role in the Indiana CTSI, and its capabilities • You know what services are available through the HUB, and what is in the works • You provide ideas that use the HUB to make your program more successful www.indianactsi.org

4. What is the Indiana CTSI HUB? • The central web portal for Indiana CTSI translational activities. • The Indiana CTSI HUB is based on the Joomla! Web 2.0 software framework (www.joomla.org), which supports modular, integrated web components or standalone applications in a model-view-controller architecture, with a MySQL backend. • A HUB is a virtual organization portal designed to support researchers pioneered by Purdue, funded by NSF, refined over the past 10 years. • HUB software is based on community source development, the HUBzero Consortium, sponsored by Purdue, IU, Wisconsin, and Clemson. It will be released as open source in April, 2010. (www.hubzero.org) www.indianactsi.org

5. How do we develop HUB services? We determine needs, then take a least cost, rapid development approach to developing HUB tools and services to meet those needs: • We prefer to use existing HUB components or Joomla! software Extensions (4281 as of 2/22/2010). • We then look for existing open source Web 2.0 applications we can easily plug into the Joomla! (eg., HUB) framework. • We then adapt existing non Web 2.0 applications into the HUB • If all else fails, we develop our own Joomla! Extensions or applications. www.indianactsi.org

6. The HUB Comes With • Integrated Search (plus we added Google Search) • Calendars, events, announcements, news and other communications • Tools to submit content for citation, peer review, tagging • Personalized HUB Pages • User Group support • Wikis and Blogs • Usage Metrics • Feedback, knowledge base, and online user support www.indianactsi.org

7. HUB Accomplishments for Years 1 and 2 • Put Clinical Trials Listings on the HUB • Added PubMed and IUSM faculty publications into integrated search (IU grants coming next) • Developed a Grants Management Tool for internal grant programs • Put the Project Development Teams (PDTs) Online • Developed a web presence for CHEP • Put the Indiana CTSI Cores online (the TTR Service Cores) • Provided Discussion Forum, Form, and Survey Tools • Authentication through Federated Identity with 6 other institutions (including NIH) • Redesigned the home page to improve usability (more coming) www.indianactsi.org

8. Current HUB Projects(partially funded by a CTSI ARRA Supplement) • Federated Identity support for all applications • Ontology tagging for all content • Alfresco Share Private Group Collaboration • i2iconnect.org Industry Partner Discovery Tool • REDCap (Research Electronic Data Capture) from Vanderbilt • OpenMRS Patient Recruitment • Online submission of next year’s annual report via forms • Next phase of usability improvements • Hosting to be moved to IU cyberinfrastructure www.indianactsi.org

9. Current HUB Projects: Cyberinfrastructure • Federated Identity support for all applications • Ontology tagging for all content www.indianactsi.org

10. Current HUB Projects: Alfresco Share Private Group Collaboration • Based on expressed need of researchers at different institutions to privately share documents for grant proposals and projects • Will support ePHI data sets • An open source product used by over 50 organizations internationally www.indianactsi.org

11. HUB Prototype: i2iconnect.org Discover Industry Licensors • Database of Industry licensing reps by specialization and disease • Partnership with Cook Medical, IURTC, IHIN, and Biocrossroads • Currently over 1,000 names in the database • Business model in development.

12. Current HUB Projects: REDCap Research Electronic Data Capture tool from Vanderbilt (pioneered by Biostatistics) • “REDCap is a secure, web-based application for building and managing online databases. Using REDCap's stream-lined process for rapidly developing databases, you may create and design databases using 1) the online method from your web browser using the Online Form Editor; and/or 2) the offline method by constructing a "data dictionary" template file in Microsoft Excel, which can be later uploaded into REDCap. REDCap provides automated export procedures for seamless data downloads to Excel and common statistical packages (SPSS, SAS, Stata, R), as well as a built-in project calendar, a scheduling module, ad hoc reporting tools, and advanced features, such as branching logic, file uploading, and calculated fields” (https://www.mc.vanderbilt.edu/victr/dcc/redcap/) www.indianactsi.org

13. Current HUB Projects: OpenMRS Patient Recruitment • Review of Open Source and Commercial Patient Recruitment systems found them to not have sufficient features or sustainability (open source) or too expensive and inflexible (commercial) • Review of Research Match national patient recruitment found it not to provide sufficient researcher access plus it did not take advantage of Indiana’s great wealth of health records data in the INPC to prequalify patients. • OpenMRS is a sustainable, flexible medical records software framework that uses HL-7 standards and already integrates well with INPC. OpenMRS development is being lead out of Regenstrief. • Scope of Work and workflows are currently being finalized www.indianactsi.org

14. The Indiana CTSI HUB Team • Bill Barnett (Lead): barnettw@iu.edu • Anurag Shankar (Technical Lead): ashankar@indiana.edu • Mike McLennan (HUB Architect): mmclenna@purdue.edu • Lilith Reeves (Chief Scientist): lreeves@iupui.edu • Bob Davis (Usability): davisrol@iupui.edu • Joe Hunt (Evaluation): johunt@iupui.edu • Samantha Scahill (Content Management): sscahill@iupui.edu • Jere Odell (Education and Bioethics): jdodell@iupui.edu • Elaine Skopelja (Library Informatics): eskopelj@iupui.edu • Beth Whipple (Library Informatics): ewhipple@iupui.edu www.indianactsi.org

15. How Can the Indiana CTSI HUB help you accomplish your program goals? Bill Barnett (barnettw@iu.edu) Anurag Shankar (ashankar@iu.edu)