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HUMAN DNA

HUMAN DNA. DNA- genetic information of the cell (Blueprint of Life) * NUCLEIC ACID *. Storing DNA. Chromatin- uncoiled DNA ( store this way during normal cell functions ) Chromosomes- DNA coiled around proteins ( stored this way when the cell reproduces ).

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HUMAN DNA

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  1. HUMAN DNA DNA- genetic information of the cell (Blueprint of Life) * NUCLEIC ACID *

  2. Storing DNA • Chromatin- uncoiled DNA (store this way during normal cell functions) • Chromosomes- DNA coiled around proteins (stored this way when the cell reproduces)

  3. In order for a cell to make a new cell it must replicate (copy) its existing chromosomes • Replicated Chromosomes • Sister Chromatids- exact copies of DNA • Centromere- connects sister chromatids Centromere

  4. Karyotype • Photograph of all chromosomes in a cell, arranged by size

  5. Types of Chromosomes • Homologous Chromosomes- two chromosomes that carry the same type of information, but are not identical • Autosomes- non-sex chromosomes • Humans: 22 pairs of autosomes + 1 pair of sex chromosomes = 23 pairs or 46 chromosomes

  6. Cell Cycle- process where cells grow and divide • Important: growth, wound healing, replace cells (old skin cells)….

  7. Cell structures involved in reproduction • Chromosomes • Spindle- protein fibers that move chromosomes • Centrioles- structures that anchor spindle at ends of the cell

  8. NORMAL CELL LIFE CYCLE • INTERPHASE • GROWTH – G1 – growth of organelles • SYNTHESIS – S – synthesis of new DNA • GROWTH – G2 – growth of proteins • MITOSIS • division of duplicated DNA • PMAT – Prophase, Metaphase, Anaphase & Telophase

  9. Stages of Mitosis • Prophase • Chromosomes present themselves; they become visible. • Metaphase • Chromosomes line up in the middle; on equator. • Anaphase • Centromeres divide. Chromosomes move apart • Telophase • Chromosomes uncoil, cytokinesis begins, and becomes two cells.

  10. Mitosis In Action! • Mitosis • Mitosis

  11. CANCER – OUT OF CONTROL CELL GROWTH • BENIGN or MALIGNANT – A difference in activity • METASTASIS – Spread away from the site of origin • Carcinoma, Sarcoma, Leukemia & Lymphoma

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