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In search of Improved Control of PRRSv

Outline. Current PRRS Control DifficultiesOverview of New TechnologiesBenefits in improving PRRS controlBest practices in evaluating tools". Current PRRS Control Difficulties (I). Herd Exposure and Closure Program works, butDifficult to remain negative" without re-infectionCost of closure per

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In search of Improved Control of PRRSv

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    1. In search of… Improved Control of PRRSv

    2. Outline Current PRRS Control Difficulties Overview of New Technologies Benefits in improving PRRS control Best practices in evaluating “tools”

    3. Current PRRS Control Difficulties (I) Herd Exposure and Closure Program works, but Difficult to remain “negative” without re-infection Cost of closure period Cost of repeated closure (parity shift, logistics) Periodic “leaking” from large herds Impact on Wean-Finish performance Managing multiple flows

    4. Current PRRS Control Difficulties (II) Multi-strain Acclimation Difficult to manage Difficult to measure / monitor Re-infection, Lateral Infections, Finishing ? Sow or System ? System Strain variation; Density ; Naďve populations

    5. Overview of New Technologies MJPRRS® Grouping Technology for differentiating PRRS viruses to improve programs for control. MJPRRS® Vaccine Technology for manufacturing of killed PRRS virus vaccine to improve antigen presentation.

    6. Smart Strain Selection™ Services Patent pending D, S, and E main groups x each 8 subgroups

    7. PRRS Isolate “demographics”

    8. Optimized level of ORF5 antigen extracts Enriched PRRSv protein components Enhanced Glycosylation dynamics U.S. Patent #7,776,537 / Foreign Patent pending

    9. MJPRRS® Vaccine Production Process

    10. Benefits resulting from these new technologies ? MJPRRS® Vaccine Rapid control of “leaking PRRS virus” Shortened interval to negative pigs after infection Improved acclimation process (gilts) Improved herd exposure-closure process Improved response to new virus infections Safer than LVI

    11. Strategies with MJPRRS® Vaccine For a tool in herd exposure and closure projects ? Incorporate MJPRRS® Vaccine with knowledge of the FARM and AREA specific PRRS strains. For improving maternal immunity for piglets ? Incorporate MJPRRS® Vaccine at 11 weeks and 3 weeks pre-farrow For a tool for gilt acclimation ? Incorporate MLV + MJPRRS® Vaccine

    12. Critical Messages MJPRRS® Vaccine is not intended to be used in naďve animals as a replacement for MLV / Serum. MJPRRS® Vaccine does allow homologous and heterologous vaccination, simultaneously. Evaluation steps can be initiated with vet-to-vet collaboration. Increased sow herd protection for less than 50 cents per pig weaned.

    13. It makes you think about what will be the standards applied to PRRS control in these areas: Sow Herd Stabilization Replacement Gilt Acclimation Piglet Protection Area Control

    14. Best Methods / Update (I)

    15. Best Methods / Update (II)

    16. Best Methods / Update (III)

    17. Best Methods / Update (IV)

    18. Best Methods / Update (V)

    19. Best Methods / Update (VI)

    20. Best Methods / Update (VII)

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