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Mi Pet-Making joint support tasty!. Presented by . Active+ THE dedicated CVS joint supplement. JOINT SUPPORT NEUTRACEUTICALS, THE KEY QUESTIONS. Are owners and members of the practice aware of the potential benefits for dogs?
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Mi Pet-Making joint support tasty! Presented by
Active+ THE dedicated CVS joint supplement
JOINT SUPPORT NEUTRACEUTICALS, THE KEY QUESTIONS • Are owners and members of the practice aware of the potential benefits for dogs? • Are you concerned about the effects of alternative long-term therapies? • Do you work hard to sell the first pot then not see repeat business? • Is compliance a problem with dogs or owners becoming bored and resistant to long term administration? • How many sales do you lose to the high street or internet?
Active+ and Healthy Pets Club • The joint supplement of choice within the HPC lifetime care medication scheme. • The dedicated joint supplement within CVS. • Allows clients 20% discount on normal cost. • Assists in facilitating long term supplement provision and client loyalty. • Acts as an overall joint support package and assists in a comprehensive multimodal osteoarthritictreatment plan.
Joint support nutraceuticals • Naturally occurring biological supplements that may confer some degree of health benefit. • High palatability enhances acceptance and facilitates compliance. • Most important components to consider are: Omega-3 series polyunsaturated fatty acids(PUFAs). Joint support nutrients glucosamine and chondroitin. • Green Lipped Muscle(GLM) contains high levels of Omega-3(PUFAs) and Glycosaminoglycans. Benefits are well documented.
P.E.T.S. Consider 4 important categories relevant to nutraceutical usage. • Product quality. • Effects. • Tolerance. • Safety.
Product quality • Ingredients of Active+ comply with Pharmacopoeia standards. • Green lipped mussel is sustainably farmed and cold processed to protect ingredient quality. • Active + chews are manufactured in a facility which is audited to strict US standards. • New packaging features enhanced airtight seal on the tub to protect the contents.
SOOTHING STIFF JOINTS AND MAINTAINING MOBILITY, WILL IMPROVE DEMEANOUR
OSTEOARTHRITIS • Is a slowly progressive irreversible disorder of moveable joints. • Cartilage deteriorates,osteophytesform,boneremodels,periarticular tissues change and inflammation occurs. • >20% of dogs over 1 year of age affected • Cartilage is aneural. • Pain is associated with periarticular tissue alteration and altered pain processing. • Owners may underestimate pain levels.
GLM-EFFICACY • On Veterinary Request further information is available regarding efficacy. • Essentially the Omega-3 PUFAs in GLM inhibit the Eicosanoids(inflammatory mediators) production from Arachidonic acid metabolism. • This is mediated by their inhibitory effects on Cyclooxygenase and Lipoxygenase. • Decreased production of harmful prostagladins and leukotrienes results. • GAG content may offer chondroprotection.
WHAT’S AN EICOSANOID? • An oxygenated derivative of a 20 carbon EFA. • >20 different Eicosanoids controlling a wide array of cellular functions especially inflammation, immunity and the central nervous system. • Parallel and competing pathways from the EFA’s. • Arachidonic Acid is the most pro-inflammatory and is an Omega-6 PUFA. • High levels of Omega-3 PUFA can help minimise the Arachidonic Acid Cascade.
Arachidonic Acid Cascade GLM: Omega-3 PUFAs (ETA,DHA) Inhibit ARACHIDONIC ACID Cyclooxygenase Cox 1,Cox 2 Lipoxygenase Lox-5 Prostaglandines Leukotrienes
SO HOW DO OMEGA 3’s WORK? • DISPLACEMENT-Dietary O3 decreases tissue concentration of AA and thus less is available to form O6eicosanoids. • COMPETITIVE INHIBITION-DGLA and EPA compete with AA for cyclooxygenase and lipoxygenase enzymes thus lowering the output of AA eicosanoids. • COUNTERACTION-Some DGLA and EPA derived eicosanoids counteract their AA derived counterparts.
PRACTICAL USEAGE GLM • In patients with early osteoarthritis (STIFF JOINTS). • In at risk categories of pet-those prone to hip/elbow dysplasia • Giant breeds as a potential preventative measure (JOINT SUPPORT) • Highly active breeds e.g. Flyball, Working dogs • Synergistically with NSAIDS e.g.carprofen. • As part of a six point plan for osteoarthritis.
The Six Point Plan • Analgesia • Bodyweight • Comfort (e.g. floor surfaces, car ramps) • Diet • Exercise • Follow-up
The Six Point Plan cont • Allows a multimodal approach to be set up easily. • All members in the team act with the same guide. • Different members have different roles to play. • The owner can be informed and guided easily. • Evolution of care progresses with the disease.
MANY THANKS FOR YOUR ATTENTION ANY QUESTIONS?