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HEART TRANSPLANTATION

HEART TRANSPLANTATION. Overall. ISHLT. 2012. J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095. NUMBER OF HEART TRANSPLANTS BY YEAR.

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HEART TRANSPLANTATION

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  1. HEART TRANSPLANTATION Overall ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  2. NUMBER OF HEART TRANSPLANTSBY YEAR NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, the presented data may not mirror the changes in the number of heart transplants performed worldwide . ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  3. NUMBER OF HEART TRANSPLANTSBY YEAR AND LOCATION NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, the presented data may not mirror the changes in the number of heart transplants performed worldwide . ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  4. AVERAGE CENTER VOLUMEHeart Transplants: January 2006 – June 2011 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  5. HEART TRANSPLANTSDonor Age by Year of Transplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  6. HEART TRANSPLANTSMedian Donor Age by Location ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  7. AGE DISTRIBUTION OF HEART TRANSPLANTRECIPIENTS BY ERA ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  8. HEART TRANSPLANTSKaplan-Meier Survival(Transplants: January 1982 - June 2010) N = 96,273 N at risk at 25 years = 112 ISHLT 2012 Survival is based on adult and pediatric transplant recipients J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  9. HEART TRANSPLANTATION Adult Recipients ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  10. DIAGNOSIS IN ADULT HEART TRANSPLANTS ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  11. ADULT HEART TRANSPLANTS Diagnosis: Cardiomyopathy vs. CAD by Location ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  12. ADULT HEART TRANSPLANTSDiagnosis by Location(Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  13. ADULT HEART TRANSPLANTSDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) ISHLT 2012 1 Based on 4/1994-2000 transplants. J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  14. ADULT HEART TRANSPLANTSDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) ISHLT 2012 1 Based on 4/1994-2000 transplants. 2 Based on 7/2004-2005 transplants. (Cont’d) J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  15. ADULT HEART TRANSPLANTSDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) 1 PRA was collected as a single percentage outside of US. Until mid-2004 PRA was collected in US as a single percentage. After this date, PRA was collected separately for Class I and Class II. 2 Based on US 2001-6/2004 transplants and non US 2001 - 2005 transplants. 3 Based on non US transplants. 4 Based on US transplants. 5 Based on 4/1994-2000 transplants. ISHLT (Cont’d) 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  16. ADULT HEART TRANSPLANTSDonor and Recipient Characteristics ISHLT (Cont’d) 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  17. ADULT HEART TRANSPLANTSDonor and Recipient Characteristics 1 Based on 4/1994-2000 transplants. 2 Based on 11/1999-2000 transplants. 3 Based on 2005 transplants. 4 Based on 5/1995-2000 transplants. ISHLT (Cont’d) 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  18. ADULT HEART TRANSPLANTSDonor and Recipient Age (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  19. ADULT HEART TRANSPLANTSDonor and Recipient Age(Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  20. ADULT HEART TRANSPLANTSPRA Distribution(Transplants: January 2006 – June 2011) ISHLT If Class I and Class II values were reported separately, the higher of the two values was used. 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  21. ADULT HEART TRANSPLANTS% of Patients Bridged with Mechanical Circulatory Support* (Transplants: January 2000 – December 2010) ISHLT * LVAD, RVAD, TAH 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  22. ADULT HEART TRANSPLANTS% of Patients Bridged with Mechanical Circulatory Support* by Year and Device Type ISHLT * LVAD, RVAD, TAH 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  23. ADULT HEART TRANSPLANTSNumber of Combined Organ Transplants Reported By Year and Type of Transplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  24. ADULT HEART TRANSPLANTS% of Combined Organ Transplants Reported By Year ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  25. ADULT HEART TRANSPLANTSDonor Age Distribution By Location (Transplants: January 2006 – June 2011) Mean/median donor age: Europe = 40.2/42.0 North America = 31.6/29.0 Other = 32.2/30.0 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  26. ADULT HEART TRANSPLANTSRecipient Age Distribution By Location (Transplants: January 2006 – June 2011) Mean/median recipient age: Europe = 49.6/52.0 North America = 52.0/55.0 Other = 48.5/51.0 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  27. ADULT HEART TRANSPLANTSRecipient BMI Distribution By Location (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  28. ADULT HEART TRANSPLANTSRecipient BMI Distribution By Diagnosis (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  29. ADULT HEART TRANSPLANTSRecipient Diabetes Mellitus Distribution By Location (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  30. ADULT HEART TRANSPLANTSRecipient Diabetes Mellitus Distribution By Diagnosis (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  31. ADULT HEART TRANSPLANTSRecipient Cigarette History By Location (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  32. ADULT HEART TRANSPLANTSRecipient Cigarette History By Diagnosis (Transplants: January 2006 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  33. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010) 1982-1992 vs. 1993-2002: p < 0.0001 1982-1992 vs. 2003-6/2010: p <0.0001 1993-2002 vs. 2003-6/2010: p <0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  34. ADULT HEART TRANSPLANTSConditional Kaplan-Meier Survival by Era (Transplants: January 1982 - June 2010) 1982-1992 vs. 1993-2002: p < 0.0001 1982-1992 vs. 2003-6/2010: p <0.0001 1993-2002 vs. 2003-6/2010: p = 0.3073 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  35. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Age Group(Transplants: January 1982 - June 2010) All pair-wise comparisons are statistically significant at p < 0.01 except 18-29 vs. 30-39 (p=0.8452) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  36. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Age Group(Transplants: January 2003 - June 2010) All pair-wise comparisons are statistically significant at p < 0.05 except 18-29 vs. 60-69; 18-29 vs. 70+, 30-39 vs. 40-49 and 60-69 vs. 70+ ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  37. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis(Transplants: January 1982 - June 2010) HALF-LIFE Cardiomyopathy: 11.4 years; CAD: 9.4 years; Congenital: 13.7 years; Retransplant: 6.0 years; Valvular: 10.9 years All pair-wise comparisons are statistically significant at < 0.001 except cardiomyopathy vs. congenital (p=0.6340). ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  38. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis Conditional on Survival to 1 Year (Transplants: January 1982 - June 2010) HALF-LIFE Cardiomyopathy: 14.0 years; CAD: 11.7 years; Congenital: 20.4 years; Retransplant: 10.7 years; Valvular: 14.3 years All pair-wise comparisons are significant at p < 0.05 except cardiomyopathy vs. valvular ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  39. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010)Diagnosis: Cardiomyopathy All comparisons are significant at p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  40. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010)Diagnosis: Coronary Artery Disease ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  41. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010)Diagnosis: Congenital No comparisons are significant at < 0.05 except 1993-2002 vs. 2003-6/2010: p = 0.0489 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  42. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010)Diagnosis: Retransplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  43. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1982 - June 2010)Diagnosis: Valvular All comparisons are significant at < 0.05 except 1993-2002 vs. 2003-6/2010 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  44. ADULT HEART TRANSPLANTSKaplan-Meier 1 Year Survival by Diagnosis(Transplants: January 2003 – June 2010) All pair-wise comparisons are significant at p < 0.05 except CAD vs. retransplant, valvular vs. congenital, valvular vs. retransplant and congenital vs. retransplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  45. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis(Transplants: January 2003 – June 2010) All pair-wise comparisons are significant at p < 0.05 except CAD vs. congenital, valvular vs. congenital, valvular vs. retransplant and congenital vs. retransplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  46. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Diagnosis Conditional on Survival to 1 Year (Transplants: January 2003 – June 2010) No pair-wise comparisons are significant at < 0.05 except cardiomyopathy vs. CAD, cardiomyopathy vs. retransplant, CAD vs. congenital and congenital vs. retransplant ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  47. ADULT HEART TRANSPLANTSKaplan-Meier Survival by PVR (Transplants: January 2003 – June 2010) 1-<3 vs. 3-<5: p < 0.0001 1-<3 vs. 5+: p = 0.3483 3-<5 vs. 5+: p = 0.1762 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  48. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Donor/Recipient Weight Ratio (Transplants: January 2003 – June 2010)For recipients with PVR: 1–<3 wood units No pair-wise comparisons are statistically significant at p < 0.05 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  49. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Donor/Recipient Weight Ratio (Transplants: January 2003 – June 2010)For recipients with PVR: 3–<5 wood units No pair-wise comparisons are statistically significant at p < 0.05 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  50. ADULT HEART TRANSPLANTSKaplan-Meier Survival by Donor/Recipient Weight Ratio (Transplants: January 2003 – June 2010)For recipients with PVR: 5+ wood units No pair-wise comparisons are statistically significant at p < 0.05 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

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