1 / 87

HEART TRANSPLANTATION

HEART TRANSPLANTATION. Pediatric Recipients. ISHLT. 2006. J Heart Lung Transplant 2006;25:893-903. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS (Transplants: January 1996 - June 2005). Number of Transplants. ISHLT. 2006. J Heart Lung Transplant 2006;25:893-903.

elias
Download Presentation

HEART TRANSPLANTATION

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HEART TRANSPLANTATION Pediatric Recipients ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  2. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2005) Number of Transplants ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  3. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2005) Number of Transplants ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  4. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant Number of Transplants NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of hearts transplanted worldwide has declined in recent years. ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  5. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS Number of Pediatric Cases Reporting ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  6. AVERAGE CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  7. DISTRIBUTION OF TRANSPLANTS BY CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  8. PEDIATRIC HEART RE-TRANSPLANTSBy Transplant YearRetransplants: January 1990 – December 2003 Year of transplant ISHLT J Heart Lung Transplant 2006;25:893-903

  9. PEDIATRIC HEART RE-TRANSPLANTSBy Intertransplant IntervalRetransplants: January 1994 - June 2005 Time Between Previous and Current Transplant ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  10. KAPLAN-MEIER SURVIVAL RATES FOR PEDIATRIC HEART RETRANSPLANTS STRATIFIED BY INTER-TRANSPLANT INTERVALRetransplants: January 1994 - June 2004 Time (years) since most recent transplant ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  11. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year) 1988-1995 1/1996-6/2005 % of Cases ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  12. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 1-10 Years) 1988-1995 1/1996-6/2005 % of Cases ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  13. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 11-17 Years) 1988-1995 1/1996-6/2005 % of Cases ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  14. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival(1/1982-6/2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  15. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival(1/1982-6/2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  16. PEDIATRIC HEART TRANSPLANTATIONConditional 5-year Kaplan-Meier Survival(1/1982-6/2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  17. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival for Recent Era(1/1999-6/2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  18. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era(1/1982-6/2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  19. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2004)Age: < 1 Year Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  20. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2004)Age: 1-10 Years Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  21. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2004)Age: 11-17 Years Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  22. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2004)Risk Factors For 1 Year Mortality N=3,341 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  23. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2004)Borderline Significant Risk Factors For 1 Year Mortality N=3,341 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  24. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2004)Risk Factors for 1 Year Mortality ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  25. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)Risk Factors for 1 Year MortalityDonor Age ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  26. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)Risk Factors for 1 Year Mortality Pre-Transplant Bilirubin ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  27. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)Risk Factors for 1 Year MortalityPre-TransplantCreatinine ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  28. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)Risk Factors for 1 Year MortalityWeight Ratio ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  29. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)Factors Not Significant for 1 Year Mortality Recipient Factors: IV inotropes, sternotomy, thoracotomy, history of malignancy, height, recent infection, age, PA pressure, cardiac output, pulmonary vascular resistance, PRA ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  30. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2004)Factors Not Significant for 1 Year Mortality Donor Factors: Gender, history of hypertension, height, clinical infection, history of diabetes Transplant Factors: CMV mismatch, ABO identical/compatible, ischemia time, HLA mismatch, transplant center volume ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  31. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2004)1-Year Predicted Survival ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  32. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Risk Factors For 5 Year Mortality ISHLT N=1,953 2006 J Heart Lung Transplant 2006;25:893-903

  33. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Borderline Significant Risk Factors For 5 Year Mortality N=1,953 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  34. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2000)Risk Factors for 5 Year Mortality ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  35. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Risk Factors for 5 Year MortalityPre-TransplantRecipient Weight ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  36. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Factors Not Significant for 5 Year Mortality Recipient Factors: History of malignancy, recent infection, bilirubin, age,PRA, pulmonary vascular resistance, PA pressures, cardiac output, sternotomy, height ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  37. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Factors Not Significant for 5 Year Mortality Donor Factors: Cause of death, history of hypertension, weight, height, age Transplant Factors: Donor/recipient weight ratio, CMV mismatch, ischemia time, HLA mismatch, transplant center volume ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  38. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Risk Factors For 5 Year Mortality Conditional on 1 Year Survival N=1,571 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  39. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Borderline Significant Risk Factors For 5 Year Mortality Conditional on 1 Year Survival N=1,571 ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  40. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2000)Risk Factors For 5 Year Mortality Conditional on 1 Year Survival ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  41. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Risk Factors For 5 Year Mortality Conditional on 1 Year SurvivalRecipient Weight ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  42. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Factors Not Significant for Conditional 5 Year Mortality Recipient Factors: History of malignancy, recent infection, hospitalized at time of transplant, bilirubin, creatinine, cardiac output, pulmonary vascular resistance, PRA, sternotomy, ventilator, VAD, age, PA pressures ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  43. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Factors Not Significant for Conditional 5 Year Mortality Donor Factors: Cause of death, history of hypertension, weight, height, age, gender, clinical infection at donation Transplant Factors: Donor/recipient weight ratio, year of transplant, CMV mismatch, transplant center volume, induction use, treated for infection prior to discharge, dialysis prior to discharge ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  44. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)5-Year Predicted Survival Conditional on Survival to 1 Year ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  45. PEDIATRIC HEART RECIPIENTSFunctional Status of Surviving Recipients (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  46. PEDIATRIC HEART RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  47. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression (Transplants: January 2001 - June 2005) % of Patients ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  48. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression (Transplants: January 2001 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  49. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2004) Conditional on Survival to 14 Days No comparisons were statistically significant. Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

  50. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2004)Conditional on Survival to 14 DaysAge: < 1 Year Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:893-903

More Related