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Stem Cell Banking - A Hope for HIV Treatment

This article examines the potential of stem cell banking as a treatment for HIV, discussing the current state of research and implication

Avantika7
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Stem Cell Banking - A Hope for HIV Treatment

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  1. Stem Cell Banking - A Hope for HIV Treatment By Avantika Singh A woman of mixed racial heritage underwent a cord blood stem cell transplant in 2017 and has been HIV-free for the past 14 months. This is the third known case of HIV remission following stem cell transplantation, according to a recent media advisory from the National Institutes of Health (NIH), which was reported at the 2022 Conference on Retroviruses and Opportunistic Infections (CROI). Around the world, stem cell therapy is increasingly studied in biomedical research. For those with various diseases and injuries, it might be an effective course of treatment. It has just been recognised as a fascinating and established scientific and academic issue HIV infection spreads easily and can last for a lifetime. Developing a thorough and efficient treatment for AIDS, its associated condition, and HIV is still a research goal. The immune system, particularly T-cells and macrophages, is where HIV is mainly spread. Treating HIV with a transplant involves giving stem cells with a mutation that makes the

  2. new immune system resistant to HIV. The patient’s immune system will naturally be able to combat HIV if it becomes active again in the body. How Does Stem Cell Banking Work? Stem cell therapy has produced outstanding results in the management of HIV and has the potential to make a big impact on HIV prevention and treatment in the future. Stem cell treatment for HIV patients aids in a decreased infection rate and a reduction in the medication dosage. It’s also interesting to note that this technique significantly improved procedure results not long after beginning antiretroviral therapy (a procedure to eliminate HIV replication). Stem cell transplantation can be used to cure several incurable diseases. They could also be used to improve the management of immunologic disorders like HIV infection and develop a fresh anti-infection therapeutic strategic plan. How Stem Cell Banking Helps HIV Patients T-helper cells (T-cells) are white immune system cells where the virus infects and reproduces. CD4 cells are another name for T-cells. HIV gradually erodes a person’s immune system by destroying more CD4 cells. Moreover, if the person cannot get antiretroviral medication, they will gradually lose the ability to control infectious diseases and infections.

  3. The most prevalent HIV subtype, HIV-1, infects immune system cells by attaching to a protein on their skin known as CCR5. A small percentage of people in the human population has a natural mutation that renders CCR5 dysfunctional and permits viral entry into the cell. In general, stem cell-based approaches to treating HIV and AIDS have recently surfaced and have become a significant research focus. Effective stem cell treatment strategies could, in theory, offer several advantages. Clinical research on stem cell therapy has revealed significant therapeutic benefits in managing various autoimmune, degenerative, and hereditary conditions. The benefits of stem cell preservation have significant advancements in treating HIV infection. Clinical investigations have demonstrated that complete tissue repair is possible when treated successfully. The first stem cell transplants were performed on HIV-positive individuals in the early 1980s who were unaware of their viral condition. Numerous HIV-positive patients worldwide with malignant tumors or other hematologic abnormalities (blood disorders) had allogeneic stem cell transplantation. Allogeneic stem cell transplantation is when a patient obtains healthy blood-forming cells (stem cells) from a donor to replace their stem cells lost due to radiation or high-dose chemotherapy treatment. People with weakened immune systems possess a high risk of contracting fatal diseases. Overtly infected cells, produced when viral DNA is incorporated into host cells’ chromosomes, are a significant barrier to eradicating HIV-1. The use of stem cells in HIV treatment is comparable to a novel strategy for restoring the

  4. body’s damaged immune system with the ultimate goal of eradicating the virus. Wrapping Up The Gurgaon-based biotech startup Cryoviva Biotech Private Limited was established by RJ Corp in 2016. Our company processes and stores high-quality umbilical cord blood stem cells for private and public donation use. We have networks in every Indian town that offer cutting-edge processing and storage equipment certified by international authorities. Our “closed bag” collection technique greatly decreases the likelihood of cord blood contamination and uses technology that has received AABB and other international certifications. To know more… Visit - https://cryoviva.in/ Follow us on social media Facebook: @CryovivaIndia Twitter: @Cryoviva_India Linkedin: @cryovivabiotech Instagram: @cryoviva_india

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