60 likes | 75 Views
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes.
E N D
pdgfra pdgfra Official Full Name Official Full Name platelet-derived growth factor receptor, alpha polypeptide Background Background This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. Synonyms Synonyms PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR- alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen- like family member A; platelet-derived growth factor receptor 2; alpha- type platelet-derived growth factor receptor; rearranged-in- hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795 Recombinant Recombinant Proteins Proteins Cell & Tissue Lysates Cell & Tissue Lysates Assay Kits Assay Kits Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price Pdgfra-1774M Recombinant Mouse Pdgfra Protein, Fc-tagged NS0 Mouse Fc +Inquiry PDGFRA-2050H Recombinant Human PDGFRA Protein, Fc/His-tagged HEK293 Human Fc/His +Inquiry PDGFRA-188H Recombinant Human PDGFRA Protein, His-tagged E. coli Human His +Inquiry
Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price PDGFRA-3560H Recombinant Human PDGFRA, His-tagged E. coli Human His +Inquiry PDGFRA-147H Recombinant Human PDGFRA Protein, DDK/HIS-tagged HEK293 Human DDK/His +Inquiry PDGFRA-1576H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide Sf 9 Insect cells Human N/A +Inquiry PDGFRA-1612H Recombinant Human PDGFRA, GST-tagged E. coli Human GST +Inquiry PDGFRA-1676H Recombinant Human PDGFRA NS0 Human N/A +Inquiry PDGFRA- 29161TH Recombinant Human PDGFRA protein, GST-tagged Insect cells Human GST +Inquiry PDGFRA- 30830TH Recombinant Human PDGFRA Human +Inquiry PDGFRA-3181H Recombinant Human PDGFRA, His tagged HEK293 Human His +Inquiry PDGFRA-384H Recombinant Human PDGFRA, GST-tagged, Active Sf 9 Insect cells Human GST +Inquiry PDGFRA-662H Recombinant Human PDGFRA, Fc-tagged, Biotinylated Human cells Human Fc +Inquiry PDGFRA-7290H Recombinant Human PDGFRA, His & GST tagged Baculovirus-Insect Cells Human His/GST +Inquiry
Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price PDGFRA-824H Recombinant Human PDGFRA, Fc tagged HEK293 Human Fc +Inquiry PDGFRA-825H Recombinant Human PDGFRA, None tagged HEK293 Human N/A +Inquiry PDGFRA- 12570M Recombinant Mouse PDGFRA Protein Mammalian Cells Mouse His +Inquiry Pdgfra-385M Recombinant Mouse Pdgfra, GST-tagged, Active Sf 9 Insect cells Mouse GST +Inquiry Pdgfra-51R Recombinant Rat Pdgfra, Fc tagged HEK293 Rat His +Inquiry Pdgfra-52R Recombinant Rat Pdgfra, His tagged HEK293 Rat His +Inquiry PDGFRA-6314C Recombinant Chicken PDGFRA Mammalian Cells Chicken His +Inquiry PDGFRA-9027Z Recombinant Zebrafish PDGFRA Mammalian Cells Zebrafish His +Inquiry PDGFRA-1147H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, His-tagged E. coli Human His +Inquiry PDGFRA-1287H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, GST-tagged Baculovirus-Insect Cells Human GST +Inquiry Involved Pathway
PDGFRA involved in several pathways and played different roles in them. We selected most pathways PDGFRA participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein MAPK signaling pathway CACNA1DA; TAB2; MAPK8A; JIP1; PRKACAA; HSP70; GADD45BB; MAP2K4A; TNFRSF1A; FGF8 Ras signaling pathway PLA2G2E; RRAS2; Kitl; PIK3CA; CALML3; GNG12; CALM1; IGF1R; PIK3R3; SHC3 Rap signaling pathway PRKD2; FGF16; DOCK4; MAPK3; MRAS; FGF19; MAP2K1; P2RY1; MAPK1; FPR1 Calcium signaling pathway CALM3; PLN; ATP2B4; PLCE1; CALM; ADRa1A; PHKA1; SPHK2; ADRB2A; CALML3 Cytokine-cytokine receptor interaction CSF1R; IL21R; Fasl; IL28RA; TNFRSF12A; CXCR7; AMHR2; CXCR5; IFNA6; TNFSF11 Phospholipase D signaling pathway MAP2K2; GRB2; PLCB4; PIK3R3; PDGFA; DGKD; GAB2; CYTH4; DGKZ; PTPN11 Endocytosis KITA; CHMP5; CSF1RA; VPS37C; ARPC4L; DNAJC6; GRK1; RAB11BA; TFR1A; STAMBP PIK-Akt signaling pathway ITGB4; FGF7; PDGFD; FOXO3; ITGB3; FGF9; PIK3CA; FGF11; Reln; RHEB Focal adhesion ACTN3B; CAPN2; IGF1R; MYL12.2; RAC3B; MYLK4; MAPK8A; ACTG1; COL1A1; AASS Gap junction GUCY1B3; HRAS; PRKCB; SOS1; PRKG2; PDGFC; GNA15.4; MAP2K2; SRC; GNAI2A Regulation of actin cytoskeleton ITGAM; ACTN3B; CDC42L2; ACTB; PFN3; RAF1; FGF11A; PPP1CA; PIP5K1A; GNG12 HTLV-I infection PRKACA; CREM; VDAC3; TLN1; WNT2; VCAM1; FZD9; CDC26; IL1R2; DVL1 Pathways in cancer IGF1R; GNG2; MAX; WNT8B; PIK3R3; PIK3CA; TPM3; PRKCA; WNT11; GNB4 MicroRNAs in cancer CCNG1; Abcb1b; RECK; RAF1; PLCG1; PTEN; CDC25A; BMPR2; DNMT3A; CD44
Glioma CALM1; PDGFB; PIK3CB; PRKCA; KRAS; PIK3CA; CALM2; PIK3R3; IGF1R; SOS1 Prostate cancer CREB3L3; INSRR; CASP9; ERBB2; ACTL6B; NDRG1; PIK3R5; PDGFC; GSK3B; IKBKG Melanoma NRAS; FGF21; MET; ARAF; Fgf15; PTEN; AKT2; MAPK1; FGF11; HGF Central carbon metabolism in cancer PDHA2; PFKM; PDGFRB; PIK3R2; PDHB; SIRT3; SLC16A3; GLS; KRAS; SLC7A5 Choline metabolism in cancer RALGDS; MAP2K2; TSC1; PDGFRA; PDGFRB; PIK3R1; PIK3CB; SP1; PDGFC; DGKZ Protein Function PDGFRA has several biochemical functions, for example, ATP binding, platelet-derived growth factor alpha-receptor activity, platelet- derived growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFRA itself. We selected most functions PDGFRA had, and list some proteins which have the same functions with PDGFRA. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function ATP binding Related Protein Related Protein NLK2; H1FNT; KIF1B; ATP8B5; ERBB3B; CDK9; NEK6; KSR1; GRK1B; PKN1B Function Function platelet-derived growth factor alpha-receptor activity Related Protein Related Protein PDGFRA Function Function platelet-derived growth factor binding Related Protein Related Protein PDGFB; PDGFRB; COL2A1; PDGFRA; COL5A1; COL4A1; COL6A1; PDGFA; COL1A2; Pdgfa&Pdgfb Function Function platelet-derived growth factor receptor binding Related Protein Related Protein PDGFRB; PDGFAB; FIGF; Pdgfa&Pdgfb; PDGFRA; IL1R1; ITGB3; ITGA5; PDGFB; PDGFAA Function Function protein binding Related Protein Related Protein RAD23A; FAH; STARD10; AGO2; COL4A3; CEBPA; ANKRD45; UBA5; RALY; SMAD4 Function Function protein homodimerization activity Related Protein Related Protein COMMD1; NR6A1; OLIG2; P2RX7; UGT1A3; CBX5; GSTA4; GOLGA5; AADAT; RQCD1 Function Function protein kinase activity Related Protein Related Protein TRIM28; CSNK2A2A; CAMKK1B; TNIKB; CAMK1DB; TNIK; SRPK1A; PDPK1A; JAK2; COL4A3BP
Functi Function Related Protein Related Protein NTRK2B; EPHB4; EPHB3A; TYRO3; ROS1; NPTNB; EPHB4B; FGFR1B; TEK; ERBB3B Function Function vascular endothelial growth factor binding Related Protein Related Protein PDGFRA; KDR; PDGFRB; NRP1 Function Function vascular endothelial growth factor-activated receptor activity Related Protein Related Protein PDGFRA; NRP2B; KDR; NRP2A; NRP1B; NRP1A; NRP1; FLT3; FLT1; NRP2 on transmembrane receptor protein tyrosine kinase activity Interacting Protein PDGFRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFRA here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFRA. PDGFB; CRK; PDGFA PDGFRA Related Articles Yi, JH; Park, BB; et al. Retrospective analysis of extra- gastrointestinal stromal tumors. WORLD JOURNAL OF GASTROENTEROLOGY 21:1845-1850(2015). Albuquerque, A; Rios, E; et al. Evaluation of clinico-pathological features and Helicobacter pylori infection in gastric inflammatory fibroid polyps. VIRCHOWS ARCHIV 465:643-647(2014). PDGFRA Related Gene Family Immunoglobulins Immunoglobulins