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Handling Newcastle disease by using the combination of Management and Nutrition. Miss Orawan Amnucksoradej Poultry nutrition specialist Vet Products Group. Newcastle Disease. Etiology : - Avian Paramyxovirus (APMV-1) Pathotypes : - Lentogenic Type - Mesogenic Type
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Handling Newcastle disease by using the combination of Management and Nutrition Miss Orawan Amnucksoradej Poultry nutrition specialist Vet Products Group
Newcastle Disease Etiology : - Avian Paramyxovirus (APMV-1) Pathotypes : - Lentogenic Type - Mesogenic Type - Velogenic Type
Economic Loss Decreased egg production Reduced egg quality and egg shell High morbidity and mortality rate Decreased weight gain Poor FCR Continuous death for 7 – 10 days
Factors for Good Performance Proper Environment Good Performance Correct Nutrition Best Management Good Health
ND and Nutrition • Good Quality Feeds • - Non-Toxic • - Clean • - High Digestibility • 2. High Palatability • 3. High nutrient density
Starch Fat Protein Nutritional Balance between Animal and Intestinal Microflora Duodenum & Jejunum Ileum Absorbed nutrients Bacteria Adapted from A. Harker (2000)
The amount of each mineral greatly affects to the absorption of other minerals
ND and Nutrition 4. Using Exogenous Feed Enzyme - helping the digestibility of nutrients 5. Decreasing anti-nutritional factors 6. Reducing feed viscosity in the GI tract 7. Immune Enhancers ( Selenium, Zinc, Vitamin E, C, etc.) 8. Physical quality of feeds - Crumble & Pellet
Non-Starch Polysaccharides in Raw Materials
Stress Physiology Stage I, Alarm reaction Adrenal medulla Epinephrine (adrenaline) Peripheral vasoconstriction Increasing respiration, blood pressure Decreasing feed intake, immune response
Stress Physiology Stage II, Stage of resistance Adrenal cortex Corticosteriods (glucagon) Accommodating stress
Stress Physiology Stage III Adrenal cortex Lost ability to produce corticosteriods (glucagon) Physical disability Death
Body Fluids and Osmotic Pressure Inside cell(40%) Extracellular cell(20%) Body fluid (60%) Fluid between tissues(15%) Blood(5%)
Body Fluid and Osmotic Pressure Increase cell electrolytes Water comes out of cell Cell wither Low electrolyte Stop when reached equailibrium passive uptake Come out Electrolyte
pH = 7 Neutral pH <7 Acid pH >7 Base Acid-Base Balance in Body Normal blood pH = 7.48~ 7.52 Homeostasis
Abnormal Acid-Base Balance 1. Acidemia---Blood pH too low Diarrhea causes loss of ions. When blood pH < 7, birds could be coma and died. 2. Alkalemia---Blood pH too high When ambient temperature was too high, birds could release CO2 by excess breathing. Then CO2 in the blood is too low. Then hens could produce more thin egg shell, get nerve system over-excited, resulting in Alkalosis, and die.
Management Strategies • Improving air ventilation in house • - Adequate oxygen supply • - Removing carbon dioxide • - Reducing pathogenic organisms • - Correct air speed • 2. Insulation (roof and wall) • 3.Effective Evaporative Cooling System
1 2 5 Damaged Blocked 3 3 4 Cleaning Blocked Blocked
Management Strategies 4. Adjusting stocking density to allow for age and weight 5. Providing adequate feeding and drinking space
Management Strategies 6. Effective Vaccination Program - Vaccination alone can not protect flocks against the overwhelming of disease challenges - Poor management practices - Vaccination Program could be based on local disease challenges
Water Quality • Providing fresh, cool, good-quality, and clean • Monitoring programs for bacteriological, toxin, and minerals contamination, and taking corrective actions
Biosecurity in farms • Visitors restriction • Isolation • Traffic Control • Sanitation ( Cleaning and disinfection) • Reducing pathogen carry over by down-time for farm cleaning • - Establish of integrated Pest Control Program
The Conclusion of Handling ND 1.Effective Vaccine Program, and every bird must receive the correct dose of vaccine 2.The Best Practice of Poultry Farm Management 3. Biosecurity in Farms 4. Correct Nutrition 5. Optimum Environment 6. Good Health