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Liver Excision-Cauterization

LEC. Liver Excision-Cauterization . Amine Hallab Kevin Mihelc, Jen Bacior, Hiroki Meguro Kelly Dympna MD, John Patzer PhD University of Pittsburgh Senior Design-BioE 1161 Tuesday January 18th, 2005. Outline. LEC. Background and Overview Design Proposal Responsibilities Achievements

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Liver Excision-Cauterization

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  1. LEC Liver Excision-Cauterization Amine Hallab Kevin Mihelc, Jen Bacior, Hiroki Meguro Kelly Dympna MD, John Patzer PhDUniversity of Pittsburgh Senior Design-BioE 1161 Tuesday January 18th, 2005

  2. Outline LEC • Background and Overview • Design Proposal • Responsibilities • Achievements • Future Work

  3. Background and Overview LEC • 1 in 10 Americans are or have been afflicted with liver disease • Treatments – Liver transplant • Liver diseases are poorly understood • Liver biopsy • common procedure for afflicted liver diagnosis • Essential tool for metabolic processes research • American Liver Foundation 2003 • Maddrey, W C, “Atlas of the Liver,” 2004, Current Medicine Inc

  4. How do surgeons take a liver biopsy ? LEC - Fully excised pig liver - Picture taken by Amine Hallab - BioScience Tower

  5. Design Proposal t t α L LEC • Liver Excision-Cauterization (LEC) • LEC Functions • To excise • To cauterize • To provide temperature control • Thermal and electrical insulation • Thermal and electrical conduction

  6. Personal Responsibilities LEC • External relations and scheduling • Design history file revision • Mathematical model • Heat Transfer • Structural design and materials • Material selection • Material structural analysis • Animal testing

  7. Personal Achievements LEC • Good foundation on liver biopsy • Met with mentors on monthly basis • Design History File • PDS, Object Tree Analysis, Function-Means • Estimated heat model for structure and materials • Stainless steal and Ceramic • Thickness of materials • Testing • Certified for animal testing • Provided a place for testing

  8. Future Work LEC • March • Compute the math model for various parameters • DHF revision • April • Final grant proposal • Animal testing • Final Presentation • January • Heat model for structural design purposes • Prototyping prerequisites • February • Prototype process • More calculation • DHF revision

  9. Acknowledgments LEC • Mark Gartner, PhD • Department of BioEngineering • LEC Group • Hiroki Meguro • Kevin Mihelc • Jen Bacior • John Patzer, PhD • Kelly Dympna, MD • Stephan Safta and Richard Miller

  10. THANK YOU

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