1 / 33

Kevin S. Williamson Yoon Group April 9, 2009

Kevin S. Williamson Yoon Group April 9, 2009. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163 US Patent 2230654. 2. 3. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163

Sophia
Download Presentation

Kevin S. Williamson Yoon Group April 9, 2009

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Kevin S. Williamson Yoon Group April 9, 2009

  2. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163 US Patent 2230654 2

  3. 3 Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163

  4. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163 O’Hagan et al. Nature 2004, 427, 561-565 4

  5. Fried, J.H.; Sabo, E.F. JACS 1953, 75, 2273-74 Fried, J.H.; Sabo, E.F. JACS1954, 76, 1455-56 5

  6. H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643 Kirk, K.L. Organic Process Research and Development 2008, 12, 305-321 6

  7. H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643 M.A. Massa et al. Bioorganic and Medicinal Chemistry Letters 2001, 11, 1625-28 7

  8. 8 H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643

  9. R = H R = F H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643 Boehm et al. J. Med. Chem. 1996, 39, 3929-3937 9

  10. Tygon & Teflon Tubing 5% F2 in N2 NaF(s) KI traps N2 REACTOR Purrington, S.T.; Woodard, D.L. JOC 1991, 56, 142 Wong et al. ACIE 2005, 44, 192-212 10

  11. Wong et al. ACIE 2005, 44, 192-212 R.E. Banks, US Patent 5,086,178 11

  12. 12 Differding, E.; Lang, R.W.; TL 1988, 29, 6087-6090

  13. 13 Shibata, N.; Suzuki, E; Takeuchi, Y. JACS 2000, 122, 10728-10729

  14. 14 Hintermann, L.; Togni, A. ACIE 2000, 39, 4359-4362

  15. 15 Shibata et al.ACIE 2005, 44, 4204-4207

  16. Beeson, T.D.; MacMillan, D.W.C.; JACS 2005, 127, 8826-8828 Steiner, D.D; Mase, N.; Barbas III, C.F.; ACIE 2005, 44, 3706-3710 16

  17. 17 Jørgensen et al. ACIE 2005, 44, 3703-3706

  18. 18 Jørgensen et al. ACIE 2005, 44, 3703-3706

  19. 19 Jørgensen et al. ACIE 2005, 44, 3703-3706

  20. Bruns, S.; Haufe, G. Journal of Fluorine Chemistry 2000, 104, 247-254 Togni et al. Eur. J. Inorg. Chem. 2006, 1397-1412 20

  21. Ferraris, J.P.; Saito, G. J. Chem. Soc. Chem. Commun. 1979, 914 Suzuki, H.; Kimura, Y. J. Fluorine Chem. 1991, 52, 341-351 21

  22. 22 Hull, K.L.; Anani, W.Q.; Sanford, M.S. JACS2006, 128, 7134-7135

  23. 23 Ball, N.D.; Sanford, M.S. JACS2009, 131, 3796-97

  24. 24 Ball, N.D.; Sanford, M.S. JACS2009, 131, 3796-97

  25. 25 Furuya, T.; Kaiser, H.M.; Ritter, R. ACIE 2008, 47, 5993-5996

  26. 26 Furuya, T.; Ritter, T. JACS2008, 130, 10060-10061

  27. 27 Furuya, T.; Strom, A.; Ritter, T. JACS 2009, 131, 1662-1663

  28. 28 Furuya, T.; Strom, A.; Ritter, T. JACS 2009, 131, 1662-1663

  29. 29 Phelps, M.E. PNAS 2000, 97, 9226-9233

  30. Top Bottom Prostate Cancer Breast Cancer 30 Phelps, M.E. PNAS 2000, 97, 9226-9233

  31. 31

  32. 32

More Related