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Ch 12 Cardiovascular Physiology. Finish Section A Begin Section B The Heart Lab is ~ 2hrs this week SPSS Abstracts due 7 Nov Editorial help before submission?. What’s missing?. Pulmonary circuit. 5 liters/min. 5 liters/min. Systemic Circuit. Resistance Vessels. Microcirculation.
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Ch 12 Cardiovascular Physiology Finish Section A Begin Section B The Heart Lab is ~ 2hrs this weekSPSS Abstracts due 7 NovEditorial help before submission?
What’s missing? Pulmonary circuit 5 liters/min 5 liters/min Systemic Circuit Resistance Vessels Microcirculation Exchange Vessels Capacitance vessels
Q=ΔP/R Flow = Pressure gradient/Resistance A version of Ohm’s Law (V=IR) Radius of arterioles regulates Q to organs Double radius … 16x flow Half radius….1/16th flow R = 8Lη/πr4 Q=ΔP πr48LηPoiseulle’s equation Smooth muscles determine radius
Cardiac Output = Heart Rate X Stroke VolumeCO = HR x SV5L/min = 72 beat/min x 70 ml/beat
Problems with valves: ….Stenosis (narrowing) →Heart Murmurs (turbulent flow past a constriction) note: origin of neonatal heat murmurs (foramen ovale) ….Prolapse (eversion) allows backflow (also generates murmurs) Bicuspid=Mitral Tricuspid Figure 12.07 Heart sounds and valve closings SemilunarValves
Figure 12.11 SA node cells spontaneously produce AP, do not have stable resting membrane potential, are Pacemaker cells
Figure 12.25 Contractility