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Accessing Information About Chemicals and Chemical Hazards. Chemical Incidents Create Various Information Needs. California: 2012 Chevron Refinery Fire. Source: abcnews.com. Texas: 2013 Fertilizer Plant Explosion. Source: U.S. Chemical Safety Board.
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California: 2012 Chevron Refinery Fire Source: abcnews.com
Texas: 2013 Fertilizer Plant Explosion Source: U.S. Chemical Safety Board
West Virginia: 2014 West Virginia Chemical Leak/Water Ban Source: wvpublic.org
Chemical Information Needed • What is this chemical? • Properties (color, odor, form, weight, solubility) • Use (fuel blending, coal washing, fertilizer production, hydrodealkylation) • Is this chemical toxic/health effects? • Humans • Animals • Plants
Chemical Information Needed (2) • What should be done for protection? • First responders, containment, clean up • Residents • Air, water, soil • If exposed, what should be done? • Fresh air, rinse eyes • Discontinue use of drinking water • Triage, emergency room/hospital, social worker • Potassium supplement, gastric lavage
Chemical Information Needed (3) • What toxicology studies have been completed? • Journal publications • Government dbases • Industry studies • What regulations and guidelines exist from government? • Have similar incidents occurred?
Searching HSDB forChemical Information Search Options: • Chemical identifiers • Name or synonym • Registry number • Query terms • Disease or health effect • Treatment method • Use
Searching HSDB forChemical Information (2) Limits Feature • Displays major sections • Expands to display many data fields • Targeted search • Multiple chemicals in results
Question/Poll Do these names represent the same chemical? • 4-Methyl-1-cyclohexanemethanol • 4-Methylcyclohexanemethanol • MCHM • 4-MCHM • p-Methylcyclohexanemethanol
Answer: Yes Types of names include: Systematic (IUPAC-International Union of Pure & Applied Chemistry) Common Trade Street
West Virginia Chemical Spill MCHM: Challenges creating a new HSDB record • 4-Methylcyclohexanemethanol • HSDB sources • Limited data available • Peer review of record • Releasing record to the public
Questions ? Presenter: Shannon M. Jordan, MPH National Library of Medicine shannon.jordan1@nih.gov