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Lecture 1 – What is Analytical Chemistry? & What is the Analytical Method?. Time out…let’s define some terms and concepts that will be very important when discussing instrumentation: Sensitivity Selectivity Detection Limit Dynamic Range. Selecting an Analytical/Instrumental
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Lecture 1 – What is Analytical Chemistry? & What is the Analytical Method?
Time out…let’s define some terms and concepts that will be • very important when discussing instrumentation: • Sensitivity • Selectivity • Detection Limit • Dynamic Range
Selecting an Analytical/Instrumental “Technique” – Things to Consider….. • What accuracy is required?Defines how much time and effort you’ll need for analysis • How much sample is available? • What is the concentration range of the analyte?{2 and 3 determine how ‘sensitive’ the method must beand how wide a range of concentrations must be} • What components of the sample cause interference?Determines “selectivity” required • What are the physical and chemical properties of the samplematrix?Some (most!) methods are phase (s,l, or g) specific • How many samples are to be analyzed?
Other things to consider…. • -speed • -ease and convenience • -skill required of operator • -cost and availability of equipment • -per-sample cost
References used: • With permission http://ull.chemistry.uakron.edu/analytical/