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We have researched to find scientific evidence to support the role of oxidative stress in many diseases to buttress the assertion that Jobelyn, being one of the most powerful natural antioxidants has a prominent role to play in maintaining wellness and treating of many diseases.
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For centuries the people of South-Western Nigeria depended on a herbal extract to cure diseases of diverse origin, including Anemia, Sickle Cell Anemia, Arthritis, Stroke, Hypertension, Diabetes, Infertility, Malaria, Cardiovascular diseases, HIV/AIDS, Leukemia, Multiple Myeloma, Breast Cancer, Hodgkin’s Lymphoma, Lupus, neurological diseases etc.
There are several sources by which the reactive oxygen species are generated. Most reactive oxygen species come from the endogenous sources as by-products of normal and essential metabolic reactions, such as energy generation from mitochondria or the detoxification reactions involving thelivercytochrome P-450 enzyme system. Exogenous sources include exposure to cigarette smoke, environmental pollutants such as emission from automobiles and industries, consumption of alcohol in excess, asbestos, exposure to ionizing radiation, and bacterial, fungal or viral infections
Jobelyn provides strong antioxidant support for red blood cells. Understanding the oxidation process, it’s easy to see how red blood cells might be particularly vulnerable to the damaging effects of oxygen radicals. Red blood cells are the body’s oxygen carriers. In the course of their 120-day lifespan, they are constantly in contact with this double-edged sword – the element that we require for life, which is also the origin of oxidation. Adding to the challenge is the fact that mature red blood cells do not have a nucleus, so they cannot produce new proteins in response to oxidative damage. One way to support red blood cell health is to prevent oxidation through strong antioxidant supplementation.
Seeing how helpful Jobelyn is for the stressed circulatory system in Sickle Cell Disease patients, it’s a small step to recognize how helpful it is for cardiovascular health in general. The medical community now views free radical oxidation and ongoing inflammation as primary contributors to heart disease, cholesterol build-up, and arteriosclerosis (severe thickening and hardening of artery walls). Just as red blood cells are exposed to lots of free radicals, so are heart and blood vessel cells. Heart cells also have the added stress of being involved in constant contraction. This muscle activity produces plenty of free radicals as a byproduct. Antioxidant protection is vital for the cardiovascular system.
Just as oxidation and inflammation are at the core of blood cell and cardiovascular health threats, this troublesome duo is also involved in causing joint degeneration and pain. The intricate connective tissue and surfaces of our joints are under constant challenge from daily use. Ongoing wear and tear, along with occasional injury, result in plenty of free radical production and inflammation. Without antioxidant support and balancing of the inflammation process, the result can be achy joints and limited range of motion.
We’ve touched on the role of Jobelyn as a powerful antioxidant and a very selective COX-2 inhibitor. Jobelyn has also demonstrated an ability to inhibit the release of pro-inflammatory proteins called cytokines. We learned how the combination of anti-inflammatory and antioxidant support results in dramatic improvements for the cardiovascular system. The same benefits can improve joint health too.
It takes a little more explanation to understand how Jobelyn supports the immune system. As with the case of red blood cell health, we need to drop down to a cellular and molecular level and think very small. It’s the antioxidant activity that is most vital for immune system support. Specifically, the extract provides components for the body to build its own super antioxidant: glutathione peroxidase. The body creates glutathione and uses it for several protective tasks including protecting certain immune system cells called CD4 T-lymphocytes. Glutathione contains selenium and three amino acids (cystein, glutamine, and tryptophan). Jobelyn contains all three of these amino acids, providing the body with some major building blocks of glutathione.
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