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Annotation: Mating type A locus

Annotation: Mating type A locus. The mating type loci of higher basidiomycetes. A locus. B locus. HD1-1. HD2-1. mfa1. pra1. MAT-1 MAT-2. pra2. mfa2. HD2-2. HD1-2. Casselton and Kues, review. Species Phylogeny. Coprinopsis cinerea Coprinopsis scobicola Coprinellus disseminatus

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Annotation: Mating type A locus

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  1. Annotation: Mating type A locus

  2. The mating type loci of higher basidiomycetes A locus B locus HD1-1 HD2-1 mfa1 pra1 MAT-1 MAT-2 pra2 mfa2 HD2-2 HD1-2 Casselton and Kues, review

  3. Species Phylogeny Coprinopsis cinerea Coprinopsis scobicola Coprinellus disseminatus Pholiota nameko Schizophyllum commune Laccaria bicolor Pleurotus djamor Phanerochaete chrysosporium Cryptococcus neoformans Ustilago maydis Ustilago hordei Microbotryum violaceum Neurospora crassa Saccharomyces cerevisiae Pneumocystis carinii Agaricales Homobasidiomycetes Basidiomycota Ustilaginomycetes/smuts Urediniomycetes/rusts Ascomycota from James TY

  4. Evolution of the A mating type locus C. cinerea 40 kb 99 kb mip b-fg ade pab Ab Ad Aa C. scobicola 39 kb mip b-fg pab C. disseminatus 32 kb mip b-fg pab S. commune 50 kb ade pab mip x P. djamor 39 kb b-fg mip mip b-fg P. chrysosporium pab ade T.Y. James, U. Kües

  5. Evolution of the A mating type locus Aa Ab Ad Aa 5kb 13kb 55kb 175kb specific conserved

  6. A mating type locus in Laccaria bicolor Aa Ab Ad 5kb Aa 13kb 55kb 175kb specific conserved

  7. A mating type locus in Laccaria bicolor FMNOR1 translocated 5kb Aa 13kb 55kb 175kb specific conserved

  8. A mating type locus in Laccaria bicolor 5kb Aa 13kb 55kb 175kb specific conserved

  9. B mating type locus in Laccaria bicolor Demo ChromoMapper L.bicolor

  10. B mating type locus in Laccaria bicolor

  11. Pheromone Receptor Receptor ACTIVATION γ β γ β cdc25 Ste6 Gpa1 Gpa1 Ras1 Ras1 GTP GDP MAPKKK cdc24 Conserved between ascomycetes and basidiomycetes Cdc42 P MAPKK Ste20 P P Plasma Membrane Cytoplasm MAPK MORPHOLOGY P pheromone P P receptor P mating type P hmg-box genes HMG P P Nucleus Mating Response Genes MAPK P HMG Known mating pheromone response pathway

  12. Conclusion • The genomic region surrounding • - the A locus is conserved on 170kb • - the B locus is not conserved between fungi • Pheromone and receptor coding gene duplication were detected • in 7 other scaffolds

  13. Acknowledgements Francis Martin Ursula Kües Alexandre Hirzel Ian Sanders

  14. C. cinerea 40 kb 99 kb mip b-fg ade pab L. bicolor 39 kb 99 kb mip b-fg ade pab A mating type locus in Laccaria bicolor C. scobicola 39 kb mip b-fg pab C. disseminatus 32 kb mip b-fg pab S. commune 50 kb ade pab mip x P. djamor 39 kb b-fg mip mip b-fg P. chrysosporium pab ade T.Y. James, U. Kües

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