Inflammatory skin disorders

1. Inflammatory skin disorders

2. eczema

3. pathophysioilogy • exact cause unknown • defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed to be important factors. • Some forms of eczema can be triggered by substances that come in contact with the skin, such as soaps, cosmetics, clothing, detergents, jewelry(contact dermatitis)

4. common in infants • often have a family history of the condition or allergic conditions asasthmaorhay fever.(atopy

5. Clinical features • Itching • Dry reddened skin • Blisters/oozing

6. sites • Adults/children-insides of the elbows, knees, and ankles. • In infants- face

7. management • Steroids –local • Antihistamines for itching

8. Contact dermatitis

9. psoriasis • Psoriasis A chronic inflammatory skin disease characterized by dry pink scaling round patches. Cause unknown Genatic and env

10. Disorganized Neutrophil accumulation Immaturity Proliferation

11. features • Erythematous, raised patches with silvery scales • Symmetric • Pruritic/ Painful • Pitting Nails • Arthritis in 10-20% of patients • Sites-extensor surfaces of knee/elbow

14. Types of psoriasis • Chronic plaque psoriasis • Erythrodermic • Guttae psoriasis • Nail pitting • pustular

15. Chronic Plaque Psoriasis

16. Erythrodermic Psoriasis

17. Nail changes

18. Guttate Psoriasis

20. management • Difficult to cure • Moisturizers • Corticosteroids • Tar/ vitamin D 3 • Drugs for itchinh

21. acne

22. Causes? • Adolecence • Emotional stress • Androgens • Family history

23. Plugging of the hair follicle w/ abnormally keratinized cells Androgen-induced sebaceous gland hyperactivity Proliferation of bacteria Inflammation Pathogenesis

24. management • Local applications • Antibiotics • Oral drugs

25. urticaria

28. Mostly by an allergic reaction • Acute urticaria can be treated with antihistamones

29. Thank you!