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Outline: Bone and Bone Tissue Cartilage Tissue Orthopedic Fracture Fixation biostable polymers Total Joint Repla

Tissues. Biomaterial: a material that can function as a whole or part of a device to treat, assist, repair or replace an tissue, organ, or function of the body.. Tissue: Define:Organ: Define: . Types of Tissues:1. Epithelial tissue: covers the body surface and forms the lining

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Outline: Bone and Bone Tissue Cartilage Tissue Orthopedic Fracture Fixation biostable polymers Total Joint Repla

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    51. Wear of UHMWPE Acetabular Cup UHMWPE generates wear particles - billions to trillions wear particles produced (150,000 per step) - Wear rate = 0.1 mm/year - most are < 1 micron - Wear particles migrate to bone and cause osteolysis ___________________________ immune system response to wear particles bone modeling balance upset osteoclasts (bone resorption): increases osteoblasts (bone building) Causes loss of bone, implant loosening Why do wear particles reduce lifetime? Bone modeling balance – think of bump on finger response to stress Loss of bone around implant stem = slippage = painWhy do wear particles reduce lifetime? Bone modeling balance – think of bump on finger response to stress Loss of bone around implant stem = slippage = pain

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