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MORE THAN JUST A HEADACHE : A CASE PRESENTATION. By: Dr. Aqeela Rasheed PGR Medical Unit-IV. Patient Profile. Patient XYZ Age/sex 23 years/female D.O.A 5.10.2012 M.O.A. Emergency.
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MORE THAN JUST A HEADACHE : A CASE PRESENTATION By: Dr. Aqeela Rasheed PGR Medical Unit-IV
Patient Profile Patient XYZ Age/sex 23 years/female D.O.A 5.10.2012 M.O.A. Emergency
Presenting Complaint C/O Headache 5 days Fever 2 days Fits 1 day Unconsciousness 1 day
History Of Present Illness • Normal delivery (♂) - 8 days back • at local hospital in Okara • Baby - healthy & delivery - uneventful • Discharged on the same day
History (contd…) • HEADACHE Gradual, Moderate, continuous, Diffuse (R > L), Dull, No aggravating/relieving factor, Vomiting, Neck pain & photophobia • FEVER Gradual, ↓grade, Continuous, no rigors /chills & Relieved by medicine temporarily
History (contd…) • FITS Recurrent, tonic clonic, Focal on Lt. side of body, later became Generalized, Urinary Incontinence & tongue bite • Altered state of consciousness
Systemic Inquiry • H/o Rt. ear discharge - 1 year • No other significant history Past History • Not significant Allergic History • No known drug allergies
Family History • No significant family history Treatment History • Not significant Socioeconomic History • Poor socioeconomic status
Personal History • House wife • Normal sleep and bowel habits • Non-smoker, non addict Gynecological History • Married for 3 years • P2 A0 • Both children are alive and healthy
General Physical Examination A woman of average physique lying in bed, unconscious, with an I.V. line secured, NGT & Foley`s are in situ: • BP: 130/70 mmHg • Pulse: 105/min • Temperature: 100°F • R/R: 18/min
CNS Examination • GCS • 5/15 (E 1,V 1, M 3) • Cranialnerves • Pupils equal & reactive to light b/l • Fundoscopy • Bilateral papillaedema • NeckStiffness ++
Ear Examination • Rightearcanal • Mild congestion &minimal debris • no defect and ulceration • No ear discharge • Leftearnormal • mastoidareas • No swelling & tenderness Systemic examination • Unremarkable
Differential Diagnosis • Meningo-encephalitis • Brain abscess • Cerebral malaria • Cerebral venous thrombosis • SAH • Ecclampsia • Puerperal sepsis
USG Abdomen Pelvis Normal scan CXR Normal
C T Scan Mastoid Lt. Rt. Rt . Lt.
Final Diagnosis CEREBRALVENOUS THROMBOSIS (Transverse And Sigmoid Sinuses) Predisposingfactors • Puerperium • Rt. Mastoiditis
Management • TO TREAT INFECTION • Antibiotics (Vancomycin, Pipericillin + Tazobactam) • ANTICOAGULATION • Heparin followed by warfarin • TO CONTROL RAISED ICP • Dexamethasone and mannitol
Management • CONTROLSEIZURES • Antiepileptics (Na valproate) • I.VFLUIDS • 0.9℅ normal saline
Management • Neurosurgical consultation • ENT evaluation
Venous Sinus Thrombosis on MRV 17 % 62% 11% 18% 41-45% 12%
Epidemiology • Female to male ratio 3:1 • Common in neonates and children • Overall incidence <1/100,000 annually
Pathogenesis • Cerebral parenchymal lesions or dysfunction • Decreased CSF absorption and raised intra cranial pressure
Etiology • Prothrombotic conditions, genetic or acquired • Oral contraceptives • Pregnancy and the puerperium • Head and Neck Infection • Malignancy • Head injury & mechanical precipitants
Clinical Features • Isolated intracranial hypertension syndrome • Focal syndrome • Encephalopathy
Take Home Message • Uncommon but serious neurologic disorder. • Imaging plays a primary role in diagnosis. • Potentially reversible.
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