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Postdural Puncture Headache and Epidural Blood Patch. Presented by R3 簡維宏. Postdural Puncture Headache (I). Any breach of the dural may result in a postdural puncture headache (PDPH) Diagnostic or therapeutic lumbar puncture Myelography spinal anesthesia epidural wet tap.
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Postdural Puncture Headache and Epidural Blood Patch Presented by R3 簡維宏
Postdural Puncture Headache (I) • Any breach of the dural may result in a postdural puncture headache (PDPH) • Diagnostic or therapeutic lumbar puncture • Myelography • spinal anesthesia • epidural wet tap
Postdural Puncture Headache (II) • Young female patients are more susceptible • Large size needles had higher PDPH rate • The same size “pencil point” needles had lower PDPH rate
Symptom & Sings of PDPH • The headache is bilateral, frontal or retro-orbital, occipital and extending to neck and may be throbbing or constant • Onset in 12-72 hours or sooner • Orthostatic, aggravated by sitting or standing and relieved by lying down flat • Frequently associated with neck, vestibular, cochlear, and ocular symptoms
Pathophysiology of PDPH • Cerebrospinal fluid (CSF) leaks from the dural puncture hole faster than its production and leads to decrease intracranial pressure, which provokes a shift of intracranial contents and traction on pain-sensitive structure in the upright position
Treatment of PDPH (I) • usually self-limited • lasting only for a few days • spontaneous revolution after bed-rest and hydration
Treatment of PDPH (II) • Conservative treatment • Bed rest, keep the patient supine • Hydration with oral or intravenous fluids • Caffeine, theophylline • Analgesics: acetaminophen, NSAID • Stool softener, soft diet
Treatment of PDPH (III) • Epidural saline injection • Epidural dextran 40 • Sumatriptan, a agonist of 5-HT
Treatment of PDPH (IV) • Epidural blood patch (EBP) • single blood patch: 90% successful rate • second blood patch: 90% successful rate for initial non-responder • Rarely surgical repair
Epidural Blood Patch • The most effective method for the treatment of postdural puncture headache • Lw complication rate • Epidural anesthesia and analgesia were not impaired after EBP • First introduced by Gormley in 1960
Method of EBP • lateral decubitus or sitting position • the same level or one level below the possible previous dural puncture site • 16 or 18 gauge epidural needle (epidural catheter) • autologous blood 10-20ml • contraindications: as spinal or epidural anesthesia
Mechanism of EBP • the volume of autologous blood injected into epidural space increases CSF pressure and, subsequently, prevents the traction of pain sensitive structure • the blood clot in the epidural space sealing the dural puncture hole prevent the CSF leakage from the dural puncture hole
Epidural Blood Patch • Discomfort or pain in the back, buttocks, or legs appear in 50-80 % patients • Indicated the existence of neural or medullary compression • Presence of these signs during injection were not a factor predicting better outcome
Predictive Factor of Failure of EBP • A large diameter of the needle: < 20 gauge • Early EBP ? < 4 days • More severe PDPH patients group • Duration per se? • Local anesthetics