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NEUROPHYSIOLOGY

NEUROPHYSIOLOGY. Anion and Cation distribution. [K+] 4mEq/l. [K+] 155 mEq/l. Fixed Anions. [Na+] 12 mEq/l. [Na+] 145 mEq/l. Resting Membrane Potential. Resting Membrane Potential. Na/K Pump Differential permeability K Diffusion Na diffusion. Local potential. Action Potential.

alec-mccullough
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NEUROPHYSIOLOGY

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  1. NEUROPHYSIOLOGY

  2. Anion and Cation distribution [K+] 4mEq/l [K+] 155 mEq/l Fixed Anions [Na+] 12 mEq/l [Na+] 145 mEq/l

  3. Resting Membrane Potential

  4. Resting Membrane Potential • Na/K Pump • Differential permeability • K Diffusion • Na diffusion

  5. Local potential

  6. Action Potential

  7. Action Potential • Depolarization to threshold • Voltage regulated gates • Repolarization • Na/K pump • All or none

  8. Nerve Impulse

  9. Saltatory Conduction

  10. Saltatory Conduction • Myelin • Speed • Temperature • Size • Efficiency • Newborns

  11. Synapses • Presynaptic Neuron • Postsynaptic Neuron

  12. Chemical Synapse • Synaptic cleft • Synaptic delay - .5-1 msec

  13. Neurotransmitters • Synaptic vesicles • Receptors • Fate of • Acetylcholine • Acetylcholinesterase

  14. Neurotransmitters • Norephinephrine • Epinephrine • Dopamine • Catecholamines • Serotonin • Amino acids, hormones

  15. Neuromodulators • Enkephalins • Endorphins

  16. Excitatory Postsynaptic Potential

  17. EPSP • Temporal Summation • Spatial Summation

  18. Inhibitory Postsynaptic Potential

  19. IPSP • Hyperpolarization

  20. Receptors

  21. Receptors • Dendrite – Very specific receptor • Stimulus • Graded • How can we determine the stimulus intensity? • Adaptation • Which sensation does not adapt?

  22. Effectors

  23. Effectors • Neuromuscular junction • End-plate potential

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