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Maggot Debridement Therapy. Give the “tiny surgeons” a chance!. History. Ancient Civilizations Maya, China, Australia Army War Surgeons Napoleon, Civil War William Baer John Hopkins Ronald Sherman House Burn Victim Episode. Importance to Healthcare . Diversity of wound types
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Maggot Debridement Therapy Give the “tiny surgeons” a chance!
History • Ancient Civilizations • Maya, China, Australia • Army War Surgeons • Napoleon, Civil War • William Baer • John Hopkins • Ronald Sherman • House • Burn Victim Episode
Importance to Healthcare • Diversity of wound types • Remove necrotic flesh • Antimicrobial properties (MRSA) • Promote Wound Healing
Wound Types • Any open purulent sore • Diabetic ulcers • Bed sores • Burns • Abscesses • Basal cell carcinoma • Vein and artery diseases • Many more
Remove Necrotic Flesh • Mouthhooks • Excretory and secretory products • Enzymes • liqification • pH
Antibiotic Resistance • ES kill bacteria • “Gut” test • Identification of antimicrobial factors • Evolution
Healing factors • E/S stimulate EGF and IL-6 • Destroy fibrin cuffs • Activate PAR system causing vasodilation • Increase circulation thus oxygen to wound
Application of Use • Make Pattern of Wound • Place maggots inside • Cover with mesh • Place gauze bandage for drainage
Cost and Insurance • $70/ 1000 larvae • Surgery • Antibiotics • Vancomycin $138/day
Results • http://www.ucihs.uci.edu/com/pathology/sherman/cases.htm