270 likes | 801 Views
Malaria Parasites. The malaria parasites of man :. Plasmodium vivax P.malariae P.ovale P.falciparum. Ⅱ Life Cycle. 1. Asexual reproduction in man. ⑴. exo-erythrocytic stage. ⑵. erythrocytic stage. 2. Sexual and asexual reproduction in mosquito. Definitive host Intermediate host
E N D
The malaria parasites of man : Plasmodium vivax P.malariae P.ovale P.falciparum
Ⅱ Life Cycle 1.Asexual reproduction in man ⑴. exo-erythrocytic stage ⑵. erythrocytic stage 2.Sexual and asexual reproduction in mosquito
Definitive host • Intermediate host • Infective stage • Mode of transmission
Ⅲ Pathogenesis & clinical manifestation 1.Pathogenesis Only erythrocytic stages of Plasmodium can produce the clinical symptoms of malaria. Synchronization of the merogony cycles The rupture of many red blood cells at once The release of merozoites, proteinaceous debris, Malarial pigment cause a peak of fever
2. Clinical Manifestation ⑴.Incubation period ⑵.Malarial attack ⑶.Relapse and Recrudescence ⑷.Anemia ⑸.Splenomegaly ⑹.Pernicious malaria
ⅣDiagnosis 1.Clinical diagnosis 2.Laboratory diagnosis Microscopy diagnosis Rapid diagnostic tests (RDTs)
Ⅴ Epidemiology 1.Geographical distribution 2.Epidemic characters
Ⅵ Prevention & Control 1.Reduction of gametocyte carriers, the source of infection. 2.Control of source of infection by drug treatment of both symptomatic patients and asymptomatic carrier is the routine method. 3.Artemisinin;Chloroquine;Quinine