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AP Bio

AP Bio. 10/04/04. Itinerary 10/05/04. Due Today: Writing an Essay for the AP Exam Topics for today Review DNA Replication Overview Messelson-Stahl Experiments In Detail Worksheet- This worksheet is due next Tuesday, 10/12. Itinerary 10/06/04. DNA Transcription DNA Translation

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AP Bio

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  1. AP Bio 10/04/04

  2. Itinerary 10/05/04 • Due Today: Writing an Essay for the AP Exam • Topics for today • Review • DNA Replication • Overview • Messelson-Stahl Experiments • In Detail • Worksheet- This worksheet is due next Tuesday, 10/12

  3. Itinerary 10/06/04 • DNA Transcription • DNA Translation • Discussion of next week’s laboratory

  4. Review • Name the four classes of biomolecules

  5. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’

  6. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide?

  7. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide?

  8. Structure of DNA/RNA (1) • Three Components • Phosphate Group • ‘Pentose Sugar’ • Nitrogenous base

  9. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the • pyrimidines?

  10. Structure of DNA/RNA (8) You need to remember these!

  11. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the • pyrimidines? • 6. What is the name of this sugar?

  12. Structure of DNA/RNA (3) Deoxyribose and Ribose are both 5 carbon sugars

  13. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the • pyrimidines? • 6. What is the name of this sugar? • 7. Base Pairing

  14. Gary Coleman

  15. Gary Coleman Guanine-Cytosine

  16. Gary Coleman Guanine-Cytosine

  17. Gary Coleman Alex Trebek Guanine-Cytosine Adenine-Thymine

  18. DNA Replication- Overview (1) • In Text- Pp 287- 297

  19. DNA Replication- Overview (1) • In Text- Pp 287- 297 • Step 1: The Double Helix is unzipped

  20. DNA Replication- Overview (1) • In Text- Pp 287- 297 • Step 1: The Double Helix is unzipped • Step 2: Each strand directs the synthesis of two new strands

  21. DNA Replication- Overview (1) • In Text- Pp 287- 297 • Step 1: The Double Helix is unzipped • Step 2: Each strand directs the synthesis of two new strands • Step 3: The individual nucleotides are connected to form two new strands

  22. DNA Replication- Overview (2)

  23. DNA Replication- Overview (3)

  24. DNA Replication- Overview (4)

  25. DNA Replication- Overview (5)

  26. Semiconservative Replication (1) Process of DNA replicationis called ‘semiconservative replication

  27. Semiconservative Replication (2) Process of DNA replicationis called ‘semiconservative replication Make sure you know this term. You’ll see it again!

  28. Semiconservative Replication (3) Process of DNA replicationis called ‘semiconservative replication This means that in each new double helix of DNA, one strand was from the parent.

  29. Semiconservative Replication (4)

  30. Semiconservative Replication (5)

  31. Semiconservative Replication (6)

  32. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature?

  33. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature? Any ideas?

  34. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature? Any ideas? Meselson-Stahl experiment tested the three hypotheses for DNA replication

  35. Semiconservative Replication (8)Meselson-Stahl Experiment

  36. Semiconservative Replication (8)Meselson-Stahl Experiment Where is the 15N found?

  37. Semiconservative Replication (9)Meselson-Stahl Experiment

  38. Semiconservative Replication (10)Meselson-Stahl Experiment

  39. Semiconservative Replication (11)Meselson-Stahl Experiment

  40. Let’s use the flashlight on DNA Replication • Remember, DNA replication is the process of making copies of DNA.

  41. Let’s use the flashlight on DNA Replication • Remember, DNA replication is the process of making copies of DNA. • When would the cell do this?

  42. Let’s use the flashlight on DNA Replication • Remember, DNA replication is the process of making copies of DNA. • When would the cell do this? • Now we need to look at the specifics of DNA replication, and the enzymes involved in each step

  43. But First, What’s an Enzyme?

  44. But First, What’s an Enzyme? • A type of Protein

  45. But First, What’s an Enzyme? • A type of Protein • Text Definition: • A class of proteins serving as catalysts, chemical agents that change the rate of a reaction without being consumed within the reaction

  46. Step 1: Separation of the Double Helix

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