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Absorption, Distribution, Metabolism and Elimination: Part I

Absorption, Distribution, Metabolism and Elimination: Part I. Joseph Graziano, Ph.D. Route of Administration Intramuscular: Intravenous:. Absorption Pattern Prompt from aqueous solutions, but slow and sustained from repository forms Immediate effects, since absorption is

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Absorption, Distribution, Metabolism and Elimination: Part I

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  1. Absorption, Distribution, Metabolism and Elimination:Part I Joseph Graziano, Ph.D.

  2. Route of Administration Intramuscular: Intravenous: Absorption Pattern Prompt from aqueous solutions, but slow and sustained from repository forms Immediate effects, since absorption is circumvented Major Routes of Drug Administration

  3. Route of Administration Oral Ingestion: Subcutaneous: Absorption Pattern Variable; depends on many factors Prompt from aqueous solutions, but slow and sustained from repository forms Major Routes of Drug Administration

  4. Other Routes of Administration • Transdermal patch • Inhalation • Intra-arterial • Intrathecal • Topical: ocular, dermal, intranasal, intravaginal routes all lead to some systemic absorption

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