Organic Compounds: Exploring Biomolecules

1. Warm - up Biochemistry Macromolecules 1. Make the following foldable out of 3 pieces of paper. 2. Label the tabs Carbohydrates(C, H,O 1:2:1) Lipids (C,H, O) Proteins (C,H,O,N sometimes C,H,O,N,S) Nucleic Acids (C,H,O,N,P) Enzymes (Proteins)

2. Glue carbohydrate picture here 3. Cut out pictures of macromolecules and glue them to the inside top flap of the labeled taps. Carbohydrates (C, H,O 1:2:1) Lipids (C,H, O) Proteins (C,H,O,N sometimes C,H,O,N,S) Nucleic Acids (C,H,O,N,P) Enzymes (Proteins)

3. Organic Compounds Organic Compounds Carbon the Backbone of Life Carbon Bonding Functional Groups Polymerization • On the back of the foldable, copy the outline. Leave room for notes.

4. Biomolecules: Carbon Compounds

5. Carbon bonding (back side) • Carbon is the most abundant element found in living things. • Carbon has 4 valence electrons which enable it to form strong covalent bonds with other atoms. • It can bond with other carbon atoms to form rings and very long chains which can be twisted and folded into millions of different, very large, and complex shapes.

6. The Element Carbon Graphite Diamond Bucky-ball Nanotube Glucose

7. Carbon the backbone of life (back of book) • All living things are made up carbon and a combination of other elements referred to as biomolecules • Biomolecules are very large molecules called macromolecules. • Each macromolecule is made up of small individual units called monomers • The macromolecules are formed by a process known as polymerization.

8. MacromoleculeGraphic Organizer All Living Things Are made up of Macromolecules Large molecules of many carbon atoms bonded together with other elements Monomers - Single units Formed by Bond to form Polymerization Polymers

9. Organic Compound/Functional Groups • Biomolecules are also known as organic compounds. • There are four groups of organic compounds found in living things: • Carbohydrates • Lipids • Nucleic Acids • Proteins

10. Carbohydrates (C, H, O) • Carbohydrates are compounds made up of carbon, hydrogen, and oxygen atoms bonded together • Single sugar carbohydrates are called monosaccharides (mono- “one”) • Two single sugars bonded together are called a disaccharide. (di- “two”) • Large macromolecules formed by the bonding of a long chain of monosaccharides are called polysaccharides. (poly- “many”)

11. Carbohydrates Functions of carbohydrates include: Living things use carbohydrates as their main source of energy Living things store carbohydrates as complex sugars known as starches Plants also use carbohydrates for structural purposes

12. Carbohydrates Did you know?? Sugars end with the suffix: -ose. Glucose, sucrose, fructose, etc.

13. Carbohydrates on a Food label There are three types of carbs that we eat: Dietary fiber Sugar Starch On a food label, there is a total # of carbs. Below that, it lists the # of grams of dietary fiber (if this is missing, there is no fiber in that food) and # of grams of sugar. Starches are not listed on food labels. To figure out the amount of starch in a food, subtract fiber and sugar from the total carbohydrates.

14. Lipids (C,H,O) • Lipids are macromolecules made mostly from carbon and hydrogen atoms • Lipids are composed of fatty acids and • glycerol • Functions: • - Lipids can be used as stored energy. • - Some lipids are important parts • of biological membranes and • waterproof coverings

15. Lipids Lipid Video • The common categories of lipids are: fats • oils waxes • steroids

16. Lipids • Sudan III solution is an indicator solution for fats & lipids. It turns red in the presence of fats & lipids.

17. Proteins (C,H,O,N) sometimes (C,H,O,N,S) • Proteins are macromolecules that contain nitrogen, carbon, hydrogen, and oxygen. • Proteins are large molecules (polymers) made up of monomers called amino acids. • Biuret Solution is an • indicator solution • for proteins. It turns • blue-violet in the presence • of proteins.

18. Proteins • Functions of proteins include: • Some proteins control the rate of the body’s chemical reactions and regulate cell processes. • Some proteins are used to form bones and muscles. • Other proteins transport substances into or out of cells or help to fight disease.

19. Nucleic Acids (C,H,O,N,P) • Nucleic acids are macromolecules containing hydrogen, oxygen, nitrogen, carbon, and phosphorus. • Nucleic acids are polymers assembled from individual monomers known as • nucleotides. • Nucleotides include of three parts: - a 5-carbon sugar - a phosphate group - a nitrogenous base

20. Nucleotides • There are five different kinds of nitrogenous bases: • Adenine • Guanine • Cytosine • Thymine • Uracil • These five different • nucleotides are used to • make the two kinds of • Nucleic Acids: • RNA and DNA.

21. Nucleic Acids • Differences in DNA and RNA • DNA is • double stranded • Bases: A, T, C and G • RNA is • single stranded • Bases: A, U, C and G

22. Nucleic Acids • Functions: • Nucleic acids store and transmit genetic information. • There are two kinds of nucleic acids, -ribonucleic acid (RNA) -deoxyribonucleic acid (DNA).

23. Indicators (write on the page of biomolecule measured) • Sudan III solution is an indicator solution for fats & lipids. It turns red in the presence of fats & lipids. • Benedict’s solution is an indicator solution for simple sugars. It changes from blue to yellow, orange or red. • Iodine solution is an indicator solution for complex sugars. It changes from brown to blue /purple. • Biuret Solution is an indicator solution for proteins. It turns blue-violet in the presence • of proteins

24. Biological Catalyst (Enzyme pg) • A catalyst is a substance that speeds up the rate of a chemical reaction. • Catalysts work by lowering a reaction’s activation energy.

25. Enzymes • Enzymes are proteins that act as biological catalysts. • Enzymes speed up chemical reactions by lowering activation energies. • Did you know?? Most enzymes end with the suffix –ase. Lactase, transaminase, phosphatase, etc.

26. Enzymes • Proteins make efficient catalysts because their shapes are very specific.

27. Biomolecules Gone Wild… Biomolecules gone wild

28. Monomer + Monomer = Polymer Dehydration synthesis Two monomers line up next to each other, and just when you think they’re going to start line dancing, a hydrogen (H) from one monomer binds with a hydroxyl group (OH) from another monomer, and voilà! A water molecule is born: H+ + OH- = H2O. 

29. Dehydration Synthesis During dehydration synthesis, two subunits, or monomers, bind to each other where they were once bound to their respective hydrogen (–H) or hydroxyl (–OH) groups. That's right. If it's a group, it gets a dash before it. This blissful union is presided over by an enzyme that is mainly there to help speed things along. The name of the process is dehydration synthesis because monomers are literally coming together and synthesizing a polymer by dehydrating, or removing a water molecule. 

30. First, what one dehydration reaction looks like:

31. Great. Let's do it again. And again. This is called dehydration synthesis.

32. Super. Why is everything so straight and awkward-looking? Fine, we will fix it. Here is the final product. Happy? (Psst. When there are zigzag lines with no atom in sight (/\/\/\), this means that carbons and hydrogens are the only connecting atoms. Yes, chemists are lazy.)

33. Large carbohydrate molecules such as starch are known as • a. lipids. • b. monosaccharides. • c. proteins • d. polysaccharides.

34. 2. Many lipids are formed from glycerol and • a. fatty acids. • b. monosaccharides. • c. amino acids. • d. nucleic acids.

35. 3. The monomers of proteins are called- • Starches • Nucleotides • Sugars • Amino acids

36. 4. Which of the following statements about cellulose is true? • a. Animals make it and use it to store energy. • b. Plants make it and use it to store energy. • c. Animals make it and use it as part of the skeleton. • d. Plants make it and use it to give structural support to cells.

37. 5. A major difference between polysaccharides and proteins is that • a. plants make polysaccharides, while animals make proteins. • b. proteins are made of monomers, while polysaccharides are not. • c. polysaccharides are made of monosaccharides, while proteins are made of amino acids. • d. proteins carry genetic information, while polysaccharides do not.