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SPDEF mRNA

1. A. SNAI2. 1 kb. B. C. MCF7/Rx2 dox cells.

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SPDEF mRNA

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  1. 1 A SNAI2 1 kb B C MCF7/Rx2dox cells Supplemental Figure 1. Potential Mechanisms Linking Runx2 to SNAI2. A, Distribution of Runx and ETS motifs within the 10-kb region upstream of the SNAI2 gene. Red and blue tics represent Runx and ETS motifs with JASPAR scores ≥10 and ≥7, respectively. B, RT-qPCR analysis of SPDEF mRNA in MCF7/Rx2dox cells treated with dox or vehicle for 48 hours. C, Runx2 ChIP-Seq results for the SPDEF locus in C4-2B/Rx2dox cells. SPDEF mRNA 0 D C

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