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In The Name of God The Merciful. Transporting Infectious Substances. Dr. Rana Amini Reference Health Laboratory. Sender. General Population. Environment. Receiver. Carrier. Who is responsible?. Shipper. Safety is your responsibility, today more than ever!. The Basis.
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Transporting Infectious Substances Dr. RanaAmini Reference Health Laboratory
Sender General Population Environment Receiver Carrier
Who is responsible? Shipper Safety is your responsibility, today more than ever!
The Basis Highest level of Safety in Transportation • Proper • Packaging • Packing • Labeling • Marking • Documentation The needed speed in Transportation Highest level of Protection
UN model regulations • ICAO • IATA • WHO • National restrictions and regulations
Mode of transport • Air (The most restrict) • Rail • Road • Marine
Road • Local surface transport • Transport of specimen from • doctor’s office to lab • Hospital to diagnostic lab • One lab to another Countries are encouraged to adopt the provisional UN model regulations In all National legislations for road transport.
Principle • The principle of transport is that the material should not have any possibility of escaping from the package under normal conditions of transport.
Hazard Classes • Explosives • Gases • Flammable Liquids • Flammable solids • Oxidizing Substances • Toxic and infectious substances and organic peroxide • Division 6.1-Toxic substances • Division 6.2-Infectious substances • Radioactive Material • Corrosives • Miscellaneous
Infectious substance • Are substances which are known or are reasonably expected to contain pathogens. • Pathogens are : defined as microorganisms( including bacteria, viruses, rickettsiae, parasites, fungi) and even prions.
Exceptions: • Dried blood spot, collected by applying a drop of blood onto absorbent material • Faecal occult blood screening test • Blood or blood components to be used for transfusion • Tissue or organs to be used for transplantation • Neutralized or inactivated pathogens • Non-pathogen microorganisms • …
Basic triple Packaging System • Primary Receptacle • Secondary Packaging • Outer Packaging
Primary Receptacles • Must be water –tight (leak proof). Glass, metal or plastic. • A water-tight , leak proof seal must be used, caps must be secured by means such as paraffin sealing tape • Note: for lyophilized substances either flame sealed glass ampoules or rubber-stoppered glass vials with metal seal
Secondary Packaging • Water-tight • Contain sufficient absorbent material to absorb the entire content • Multiple primary receptacles may either be wrapped individually or separated to prevent conatct between the conatiners.
Outer Packaging • Must be rigid • Withstand several specific tests • Resistant to water
Marking and labeling • Durable • On the external surface • Readily visible • Able to withstand weather exposure • Proper name , address and telephone of the shipper
Training Familiarization Job specific
Bio-security Refers to institutuional and personal security measures designed to prevent the loss, theft, misuse or intentional release of pathogens and toxins
Biosafety and Biosecurity • Appropriate policies and measures applied to minimize relevant biological risks • (Minimize the risks don’t waste time debating the definitions)
Risk assessment and Policy For ex. Polio
Biological threats to: • Agriculture, fisheries & forests • Natural resources • International and domestic trade • Tourism & Lifestyle • Economy & infrastructure • Public health & safety
Bio-security program • Comprehensive program • Cover the whole field of activities • An updated inventory • Level of access • Description of use • Documentation of any transfers
Risk management approach A modern risk management framework (SA/SNZ 1999) Establish the context Identify risks Communicate and Consult Monitor and Review Analyse risks Evaluate risks Treat risks International risk management methods can be applied to all areas of economies, community and environment
Training Identifying the rationale of these precautions