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Surgical resectionPathology assessment and estimation of riskTreatment based upon classical TNM factorsPostoperative concurrent chemoradiation. OLD APPROACH TO RECTAL CANCER. NIH consensus conference. Adjuvant therapy for patients with colon and rectal cancer JAMA, Sep 1990; 264: 1444 - 1450. .
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2. Surgical resection
Pathology assessment and estimation of risk
Treatment based upon classical TNM factors
Postoperative concurrent chemoradiation
OLD APPROACH TO RECTAL CANCER
3. The concept of TME surgery
Optimal staging by MRI
Integration of knowledge in a multidisciplinary team approach
Selection of patients for preoperative therapy
RECENT CHANGES IN RECTAL CANCERDIAGNOSIS AND THERAPY
7. PREOPERATIVE STAGING OF RECTAL CANCER WITH MRI
8. PREOPERATIVE STAGING OF RECTAL CANCER
12. Improved coordination of care
To consider each case from a variety of perspectives.
Patients are more likely to be offered a range of types of treatment at appropriate times
A supportive environment where professionals can share their concerns
Surgeons receive feedback from pathologists and other team members on the results of their work
Optimal setting for clinical research
13. Experienced imaging specialist, particularly on MRI
At least two well trained TME surgeons
Pathologist able to report on specific requirements
Radiation Oncologist with focused interest in rectal cancer
Medical Oncologists
Clinical Nurse specialist
Other non core members
14. Discussion of all new cases before surgery
Discussion of MRI data
Selection of patients for preoperative therapy
Discussion of pathology report, stressing the assessment of the surgical plane and CRM
Selection for postoperative therapy
Detailed discussion of any relapse during follow up
Yearly audits of all activities and results
15. Systemic Staging: Thorax and abdominal CT
Local Staging: Rectoscopy, Endorectal US, DRE
MRI* has a key role in defining:
Prediction of CRM involvement
Tumor within 1 mm of the mesorectal fascia
T3-4 arising from below the level of origin of the levator muscles
Extramural spread >5mm
Extramural Vein Invasion
Peritoneal involvement
20. MRI Staging
MDT discussion
Preoperative chemoradiation if indicated
TME Surgical resection
Pathology assessment and estimation of risk
Postoperative chemotherapy if indicated
CURRENT APPROACH TO RECTAL CANCER
21. MULTIDISCIPLINARY TEAM FOR COLORECTAL CANCER UNIVERSITY HOSPITAL VALENCIA MRI: Salvador Campos
Pathology: Samuel Navarro
Surgery: Eduardo García Granero, Pedro Esclapez, Alejandro Espí, Blas Flor, Estephanie García-Botello, Tina Juan, Salvador Lledó
Radiation Oncology: Ana Hernández, Pepe López Torrecilla
Medical Oncology: Edith Rodríguez, Isabel Chirivella (Family Cancer Unit), Ana Bosch, Paloma Martín, Andrés Cervantes