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Prevalence of chronic constipation in general population Dr. Vicente Garrigues Gastroenterology Unit Hospital Uni

Prevalence of chronic constipation in general population Dr. Vicente Garrigues Gastroenterology Unit Hospital Universitario LA FE Valencia - Spain. Gastroenterologist since 1985. Working in a 1.500-bed University Hospital.

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Prevalence of chronic constipation in general population Dr. Vicente Garrigues Gastroenterology Unit Hospital Uni

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  1. Prevalence of chronic constipation in general population Dr. Vicente Garrigues Gastroenterology Unit Hospital Universitario LA FE Valencia - Spain

  2. Gastroenterologist since 1985. • Working in a 1.500-bed University Hospital. • Interested in Digestive Functional Disorders and in Epidemiology & Statistics. • At present, Head of Education of the Hospital

  3. Learning objectives • To know current definitions of chronic constipation. • To find out the prevalence of constipation. • To know which variables are associated to constipation.

  4. Performance objectives • To select a sample for a prevalence study. • To perform statistics in a prevalence study. • To understand the meaning of likelihood ratios.

  5. Aims • Evaluate the prevalence of chronic constipation in the general population. • Assess agreement among several diagnostic criteria of constipation

  6. Aims • Evaluate the diagnostic accuracy of self-reported definition of constipation; and of symptoms included in Rome II criteria. • Identify factors associated to chronic constipation

  7. Definition of constipation • Self-reported by subject • Rome criteria • Rome II criteria

  8. Study subjects. Selection of population Target population: General population from the town of Aldaya: 23.425 inhabitants Elegible population: subjects aged between 18 and 65 years: 15.696 subjects

  9. Study subjects. Selection of sample. For an expected prevalence of 20 + 4% (95% C.I.): 375 subjects were needed. Sampling procedure. Systematic, age-stratified sampling was performed, selecting 506 subjects.

  10. Questionnaire A validated questionnaire with 21 items was mailed –up to 6 times- to sampled subjects. Items allowed diagnosis of constipation and evaluated associated variables.

  11. Response 349 subjects (71.5%) replied.

  12. Prevalence of constipation

  13. Prevalence of constipation

  14. Prevalence of constipation

  15. Agreement among criteria Self-reported Kappa: 0.68 95%-IC: 0.59- 0.77

  16. Agreement among criteria Self-reported Kappa: 0.55 95%-IC: 0.44- 0.65

  17. Agreement among criteria Rome Kappa: 0.71 95%-IC: 0.61- 0.81

  18. Diagnostic accuracy of Rome II qualifying symptoms Gold-standard: self-reported

  19. Accuracy of self-reported and Rome II symptoms Gold-standard: Rome II

  20. Variables associated with constipation

  21. Conclusions Constipation is highly prevalent, especially in women. Different prevalence rates are observed using different criteria,although agreement is acceptable. Anal blockage, straining and hard stools show the greatest diagnostic accuracy.

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