1 / 10

T inatin Bukia

T inatin Bukia. Synthesis some of B ioactive Adamantane F ragment C ontaining N ew P eptides V ia Ugi- R eaction. Ugi reaction. Ugi reaction mechanism. Potential peptide and protein drug

aquarius
Download Presentation

T inatin Bukia

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tinatin Bukia Synthesis someof Bioactive Adamantane Fragment Containing New Peptides Via Ugi- Reaction

  2. Ugi reaction

  3. Ugi reaction mechanism

  4. Potential peptide and protein drug Amylin Diabetes and nutrition regulation CalcitoninHyperoalcemia Ciclosporin Immunosuppressant Desmopressin Diabetes Epceitin Anemia Glucagon Hyperoalcemia FilgrastimNeutropenia MolgramostinNeutropenia Octreotide Pancreatitis Urofollitin Infertility Vasopressin Diabetes

  5. Adamantan containing preparations

  6. R1=C6H5CH2; C6H5; n-C4H9; Ad; R2=i-C3H7; C4H9; R3=CH2-COOC2H5; C6H5;

  7. Research subject :

  8. Conclusion It is known by general the role of peptides in the modern medical practice. They are characterized wide spectrum ofbiological activity, which are widly used in the drug manufacture. By the biological activity are distinguished adamantane containing organic compounds, they are widely used in medicine as antiviral, antimicrobial, anticancerogenic, anticataleptic, immunotropic, neuropsychotropic and for a cure of other diseases. thus , the research and synthesis of adamantane containing new peptides is perspective and actual. The aim of our project Is to be continued research work about the syntheses of bioactive adamantane containing new peptides via Ugi- reaction.

  9. THANK YOU ALL FOR ATTENTION!!!

More Related