Ageless Body, Timeless Mind .

1. Ageless Body, Timeless Mind. Quality of life While Quality of Life has long been an explicit or implicit policy goal, adequate definition and measurement have been elusive. Diverse "objective" and "subjective" indicators across a range of disciplines and scales, and recent work on subjective well-being surveys and the psychology of happiness have spurred renewed interest.

2. According to Gary Null (PhD), Carolyn Dean (MD), Martin Feldman (MD), Debora Rasio (MD) and Dorothy Smith (PhD), the American Medical System is the Leading Cause of Death and Injury in the United States. They suggest that a definitive review and close reading of medical peer-review journals, and government health statistics shows that American medicine frequently causes more harm than good.

3. Doctors are taught that mistakes are unacceptable. Medical mistakes are therefore viewed as a failure of character and any error equals negligence. We can see how a great deal of sweeping under the rug takes place since nobody is taught what to do when medical error does occur the "infallibility model" of medicine leads to intellectual dishonesty with a need to cover up mistakes rather than admit them.

4. The number of people exposed to unnecessary hospitalization annually is 8.9 million.The total number of iatrogenic [induced inadvertently by a physician or surgeon or by medical treatment or diagnostic procedures] deaths is 783,936. The 2001 heart disease annual death rate is 699,697the annual cancer death rate is 553,251c it is evident that the American medical system is the leading cause of death and injury in the United States. As few as 5% and only up to 20% of iatrogenic acts are ever reported. Dr. Leape, in 1994, said his figure of 180,000 medical mistakes annually was equivalent to three jumbo-jet crashes every two days. Our report shows that six jumbo jets are falling out of the sky each and every day

5. What we must deduce from this report is that medicine is in need of complete and total reform: from the curriculum in medical schools to protecting patients from excessive medical intervention. It is quite obvious that we can't change anything if we are not honest about what needs to be changed. This report simply shows the degree to which change is required.

6. Money can't buy you love but it can buy you any "scientific" result you want. Cynthia Crossen, writer for the Wall Street Journal in 1996, published "Tainted Truth: The Manipulation of Fact in America. If clinical trials become a commercial venture in which self-interest overrules public interest and desire overrules science, then the social contract which allows research on human subjects in return for medical advances is broken.

7. When the boundaries between industry and academic medicine become as blurred as they are now, the business goals of industry influence the mission of medical schools in multiple ways." She did not discount the benefits of research but said a Faustian bargain now existed between medical schools and the pharmaceutical industry. The ABC report said that one measurable tie between pharmaceutical companies and doctors amounts to over $2 billion a year spent for over 314,000 events that doctors attend

8. The literature on medical error is sparse and we are only seeing the tip of the iceberg when errors are specifically sought out, reported rates are "distressingly high." He cited several autopsy studies with rates as high as 35% to 40% of missed diagnoses causing death. He also commented that an intensive care unit reported an average of 1.7 errors per day per patient, and 29% of those errors were potentially serious or fatal. Unlike a jumbo-jet crash, which gets instant media coverage, hospital errors are spread out over the country in thousands of different locations.

9. The literature on medical error is sparse and we are only seeing the tip of the iceberg when errors are specifically sought out, reported rates are "distressingly high." He cited several autopsy studies with rates as high as 35% to 40% of missed diagnoses causing death. He also commented that an intensive care unit reported an average of 1.7 errors per day per patient, and 29% of those errors were potentially serious or fatal. Unlike a jumbo-jet crash, which gets instant media coverage, hospital errors are spread out over the country in thousands of different locations.

10. The new old age: We are victims of sickness, aging, and death by gaps in our self-knowledge” and this lack of awareness of the real I “leads to loss of control over the end product of intelligence, the human body.” “Chronological Age – how old you are by the calendar; Biological Age – how old your body is in terms of critical life signs and cellular processes, i.e., how time has affected your organs and tissues compared to other people of your chronological age; and Psychological Age – how old you feel you are.”

11. 'Defeating Entropy', Stress, Sorrow, and Negative Emotions that lead to disease, aging, and death. However, he says, it is not stress that kills but the body’s coping mechanism that is to be blamed. Some people thrive under stress while some crumble. It is not the stressful event but “your inner appraisal of it and your body’s reaction” that allow stress to take its toll

12. Merely being a centenarian is not the triumph of life but to achieve pure wisdom at that stage is the true aim. Human body is subject to entropy and decay but with a little effort we can have an ageless body, a mature soul, and a timeless mind that are our “links to immortality.”

13. ವೈದ್ಯ ಶಿಕ್ಷಣಕ್ಕೆಕಾಯಕಲ್ಪವೈದ್ಯಕೀಯಶಿಕ್ಷಣದಕಾರ್ಯನಿರ್ವಹಣೆನೋಡಿಕೊಳ್ಳುತ್ತಿದ್ದಭಾರತೀಯವೈದ್ಯಕೀಯಮಂಡಳಿಗೆ (ಎಂಸಿಐ) ಕಾಯಕಲ್ಪಮಾಡುವಕೇಂದ್ರಸರ್ಕಾರದನಿರ್ಧಾರಸ್ವಾಗತಾರ್ಹ. ಎಂಸಿಐನಹಿಂದಿನಅಧ್ಯಕ್ಷಕೇತನ್ದೇಸಾಯಿಭ್ರಷ್ಟಾಚಾರಬಯಲಿಗೆಬಂದಹಿನ್ನೆಲೆಯಲ್ಲಿಕೇಂದ್ರವುಸುಗ್ರೀವಾಜ್ಞೆಯೊಂದನ್ನುಹೊರಡಿಸುವಮೂಲಕಮಂಡಳಿಯನ್ನೇವಿಸರ್ಜಿಸಿದೆ. ಸರ್ಕಾರದ ಈ ಕ್ರಮವನ್ನುಗಮನಿಸಿದರೆ 76 ವರ್ಷದಷ್ಟುಹಳೆಯದಾದಇಡೀಮಂಡಳಿಯೇಭ್ರಷ್ಟವ್ಯವಸ್ಥೆಯಾಗಿತ್ತೆಂಬಬಲವಾದಶಂಕೆಗೆಎಡೆಕೊಟ್ಟಂತಾಗಿದೆ.

14. ಈ ಮಂಡಳಿಯುನಿರ್ವಹಿಸುತ್ತಿದ್ದಕಾರ್ಯವನ್ನುಒಂದುವರ್ಷದವರೆಗೆನೋಡಿಕೊಳ್ಳಲುದೇಶದವಿವಿಧಭಾಗಗಳಆರುಮಂದಿತಜ್ಞವೈದ್ಯರಸಮಿತಿಯೊಂದನ್ನುರಚಿಸಿರುವುದುಸದ್ಯಕ್ಕೆಒಂದುತಾತ್ಕಾಲಿಕವ್ಯವಸ್ಥೆ. ವೈದ್ಯಕೀಯಕಾಲೇಜುಗಳಿಗೆಮಾನ್ಯತೆ, ಮಾನ್ಯತೆಯನವೀಕರಣಅಥವಾರದ್ದು, ವೈದ್ಯಕೀಯವೃತ್ತಿಕೈಗೊಳ್ಳಲುನೊಂದಾಯಿಸಿಕೊಳ್ಳುವವರಕಾರ್ಯದಮೇಲೆಕಣ್ಣಿಡುವುದುಸೇರಿದಂತೆದೇಶದಲ್ಲಿವೈದ್ಯಕೀಯಶಿಕ್ಷಣದಗುಣಮಟ್ಟಕಾಯ್ದುಕೊಳ್ಳುವಕಾರ್ಯವನ್ನುಎಂಸಿಐನಿರ್ವಹಿಸುತ್ತಿತ್ತು

15. ದೇಸಾಯಿಅವರಂತಹಭ್ರಷ್ಟರಿಂದಾಗಿಎಂಸಿಐಕಾರ್ಯನಿರ್ವಹಣೆಯನ್ನುಶಂಕಿಸುವಂತಾದದ್ದುದುರಂತ. ಈ ಮಂಡಳಿಗೆಪರ್ಯಾಯವಾಗಿಹೊಸದೊಂದುಸಂಸ್ಥೆಯನ್ನೇಹುಟ್ಟುಹಾಕಲುಕೇಂದ್ರಸರ್ಕಾರವು 1956ರ ಸಂಬಂಧಿಸಿದಕಾಯ್ದೆಗೆತಿದ್ದುಪಡಿತರಲುಹೊರಟಿದೆ. ಇಂತಹಬದಲಾವಣೆತರುವುದಕ್ಕಾಗಿಎಂಸಿಐವಿಸರ್ಜನೆಅನಿವಾರ್ಯವಾಗಿತ್ತು. ಆದರೆಕೇಂದ್ರದ ಈ ಕ್ರಮವನ್ನುಭಾರತೀಯವೈದ್ಯಕೀಯಸಂಸ್ಥೆ (ಐಎಂಎ) ವಿರೋಧಿಸುತ್ತಿರುವುದುವಿಪರ್ಯಾಸ.

16. ಹೊಸದಾಗಿನೇಮಕಗೊಂಡಿರುವಸಮಿತಿಯಲ್ಲಿರುವವರುವೃತ್ತಿಯಲ್ಲಿಪ್ರಾವೀಣ್ಯತೆಪಡೆದವರಷ್ಟೇಅಲ್ಲ, ಉತ್ತಮಆಡಳಿತಗಾರರೂಆಗಿದ್ದಾರೆ. ಅವರುಮಾಡಬೇಕಾದಮೊದಲಕೆಲಸವೈದ್ಯಕೀಯಶಿಕ್ಷಣಕ್ಷೇತ್ರಕ್ಕೆಸಂಬಂಧಿಸಿದಂತೆಹೊಸನೀತಿಯನ್ನುರೂಪಿಸುವುದಾಗಿದೆ. ಭ್ರಷ್ಟಾಚಾರಕ್ಕೆಮತ್ತುಅಕ್ರಮಗಳಿಗೆಎಡೆಯಿಲ್ಲದೆ ಈ ನೀತಿಯನ್ನುಕಟ್ಟುನಿಟ್ಟಾಗಿಜಾರಿಗೊಳಿಸುವಂಥಆಡಳಿತಾಂಗವನ್ನುಅವರುರಚಿಸಬೇಕಿದೆ. ಎಂಸಿಐಆಡಳಿತಹೊಣೆಹೊತ್ತವರುಪ್ರಾಮಾಣಿಕರೂ, ದಕ್ಷರೂಆಗಿದ್ದರೆನೀತಿಯನ್ನುಜಾರಿಗೊಳಿಸುವುದುಅಷ್ಟುಕಷ್ಟವೇನಲ್ಲ. ಉದ್ದೇಶಿತನೀತಿಒಂದುವರ್ಷದಅವಧಿಯದೇಆಗಿದ್ದರೂಅದುಮುಂದಿನಕ್ರಮಗಳಿಗೆಮಾರ್ಗದರ್ಶಿಯಾಗುವಂತೆನೋಡಿಕೊಳ್ಳಬೇಕಿದೆ. ವೈದ್ಯಕೀಯಶಿಕ್ಷಣದಲ್ಲಿನಕೊಳೆಯನ್ನುತೊಳೆಯುವಕಡೆಯೂಕೇಂದ್ರಸರ್ಕಾರಗಮನನೀಡಬೇಕು

17. The process of change is more complicated today than in the past. The physician must practice ethically in an environment of enormous technological complexity, where authority has shifted to insurers and risk, to the profession; where ethnic, cultural, and religious pluralism, especially in the “human life” issues, divide the profession and the public; where moral skepticism is the order of the day; and where law, economics, and patient autonomy demand to be heard at the bedside.

18. Diabetes: Diabetes like a wildfire out of control .Over one of every three Indian children born since 2000 is expected to develop diabetes, and soon it may be closer to one in two in USA.Most people underestimate the seriousness of diabetes one study found that 7% of type 2 diabetics will have an amputation within 14 years of diagnosis. Many of these life threatening complications appear after 10 to 20 years, but if the rates of childhood diabetes continue to skyrocket, half of our young people could be facing certain permanent disability by the time they are 35-40 years old!

19. Over the next decade, diabetes prevalence is expected to grow by 25 per cent, which is largely driven by the rising prevalence of obesity and inactivity. The World Health Organization (WHO) estimates that While in 1985, 30 million people had diabetes worldwide; the number rose to 150 million in 2000, 285 million in 2010 and is estimated to be 435 million - 7.8% of the adult world population by 2030. India has the highest number of diabetics in the world

20. The prevalence of Diabetes in urban population is 17% and in rural it is 2.5%. This indicates impact of life style and nutritional habits by next year, the country will be home to 50.8 million diabetics, making it the world's unchallenged diabetes capital. And the number is expected to go up to 87 million -- 8.4% of the country's adult population -- by 2030. a)Stem cell therapy • This should be theoretically used for Type 1 Diabetic patients in whom insulin secreting cells are destroyed.

21. Stem cells therapy is potentially useful in diabetic foot ulcers which are difficult to treat by conventional methods. It is expected that stem cell treatment will increase new vessels in ulcer area so that healing is accelerated. We have been using this treatment now for the first time in India.Pancreas/ Islet cells (insulin producing cells) transplant

22. Early and intensive intervention in patients with diabetes reduces the risk of microvascular and macrovascular complications and disease progression. Current challenges in diabetes management include: (1) optimizing the use of currently available therapies to ensure adequate glycemic, blood pressure, and lipid control and to reduce complications; (2) educating patients on diabetes self-management; (3) improving patient adherence to lifestyle and pharmacologic interventions; (4) reducing barriers to the early use of insulin; and (5) improving the delivery of health care to people with chronic conditions.

23. Beta Cell Programming for Treatment of Diabetes Regenerating a functional beta cell mass is thus a major goal in biomedicine and in society. Beta cell grafts prepared from human pancreases can cure the disease but development of this form of beta cell therapy is hindered by shortage in donor organs. The consortium with leading teams in molecular, developmental and functional biology has worked out an integrated program to generate insulin-producing beta cells in therapeutic quantities and established interactions to translate knowledge to associated bioindustry and multicenter clinical trials, as well as to society

24. Nature's biologic program to develop and preserve a functional beta cell mass throughout life is taken as platform for directing strategies towards laboratory production of a therapeutic beta cell mass. Beta cells will be derived from embryonic stem cells, liver, intestinal and pancreatic exocrine cells. Functional genomics will be used to compare phenotypes of beta cells from new sources with those isolated from the pancreas. The consortium considers its plan realistic in its perspective to help develop a cure for diabetes by (re)programming cells for beta cell therapy.

25. Nanoparticle Vaccine Used to Cure Type 1 Diabetes Using a sophisticated nanotechnology-based "vaccine," researchers were able to successfully cure mice with Type 1 diabetes and slow the onset of the disease in mice at risk for the disease.

26. The researchers were looking to specifically stop the autoimmune response that causes Type 1 diabetes without damaging the immune cells that provide protection against infections -- what is called an "antigen-specific" immunotherapy.  Type 1 diabetes is caused when certain white blood cells (called T cells) mistakenly attack and destroy the insulin-producing beta cells in the pancreas

27. The researchers developed a unique vaccine comprised of nanoparticles, which are thousands of times smaller than the size of a cell.  These nanoparticles are coated with protein fragments -- peptides -- specific to Type 1 diabetes that are bound to molecules (MHC molecules) that play a critical role in presenting peptides to T cells.  The nanoparticle vaccine worked by expanding the number of peptide-specific regulatory T cells that suppressed the aggressive immune attack that destroys beta cells

28. Medical professionalism goes wider than treating patients effectively, it consists of building and maintaining relationships, trust, understanding, honesty, confidentiality and in fact humanity.  As a profession the focus of our attention must always be the patient.  We must learn to subsume our personal interests and those of the fellows and members we represent in the interests of our patients.  We must listen to the views of our trainees – many of whom have expressed frustration in the leadership of the profession – to ensure that the next generation can rekindle the vocation which encouraged us to pursue a career in medicine

29. Patients must be able to trust doctors with their lives and health. Make the care of your patient your first concern, Treat patients politely and considerately and Listen and respond to their concerns and preferences Give patients the information they want or need in a way they can understand Respect patients' right to reach decisions with you about their treatment and care. Be honest and open and act with integrity.

30. Be competent, keep your knowledge and skills up to date, Establish and maintain good relationships with patients and colleagues, recognize and work within the limits of your competence respect the patient's right to seek a second opinion; keep clear, accurate and legible records, reporting the relevant clinical findings, the decisions made, Florence Nightingale's maxim—“first and foremost - do no harm."