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Lower-limb amputation and body weight changes in men

Lower-limb amputation and body weight changes in men. Alyson J. Littman, PhD; Mary Lou Thompson, PhD; David E. Arterburn, MD, MPH; Erin Bouldin, PhD; Jodie K. Haselkorn, MD; Bruce J. Sangeorzan, MD; Edward J. Boyko, MD. Aim

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Lower-limb amputation and body weight changes in men

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  1. Lower-limb amputation and body weight changes in men Alyson J. Littman, PhD; Mary Lou Thompson, PhD; David E. Arterburn, MD, MPH; Erin Bouldin, PhD; Jodie K. Haselkorn, MD; Bruce J. Sangeorzan, MD; Edward J. Boyko, MD

  2. Aim • Evaluate relationship between lower-limb amputation (LLA) and body weight change over 3 yr. • Examine extent to which weight change varies by level of amputation and body-mass index before surgery. • Relevance • Excess body weight is a major concern for people with LLA, but little is known about relationship between LLA and subsequent changes in weight.

  3. Method • Retrospective cohort study using clinical and administrative databases: • 759 males with amputation. • 3,790 nondisabled persons frequency-matched on age, body mass index, diabetes, and calendar year from 8 Pacific Northwest VA medical facilities. • Estimated and compared longitudinal % weight change from baseline up to 39 mo of follow-up.

  4. Results • Weight gain in the 2 yr after amputation was significantly more in: • Men with amputation than without. • Men with transtibial or transfemoral amputation (8%–9% increase) than in men with partial foot amputation (3%–6% increase). • Generally, % weight gain peaked at 2 yr, followed by some weight loss in 3rd year.

  5. Conclusion • LLA is often followed by clinically important weight gain. • Future studies are needed to: • Understand reasons for weight gain. • Identify intervention strategies to prevent excess weight gain and its deleterious consequences.

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