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Valentina Di Francesco Senior Program Officer for

Valentina Di Francesco Senior Program Officer for Bioinformatics, Structural Genomics and Systems Biology email: vdifrancesco@niaid.nih.gov Microbial Genomics and Advanced Technologies DMID, NIAID, NIH. Systems Biology for Infectious Diseases Research. Goals:

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Valentina Di Francesco Senior Program Officer for

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  1. Valentina Di Francesco Senior Program Officer for Bioinformatics, Structural Genomics and Systems Biology email: vdifrancesco@niaid.nih.gov Microbial Genomics and Advanced Technologies DMID, NIAID, NIH

  2. Systems Biology for Infectious Diseases Research Goals: To establish large scale, coordinated Systems Biology Programs that utilize a combination of computational and experimental methodologies to conduct research projects to analyze, quantify, model and predict the interacting networks of cellular molecular components of microbial organisms and their interactions with the host cells. To utilize the existing high-throughput “-omics” technologies, such as functional genomics, proteomics, metabolomics, lipidomics. To make research data, analysis tools, modeling algorithms, reagents and experimental protocols publicly and freely accessible to the scientific community in publicly available repositories. To enhance knowledge of the overall complexity of the biological, biochemical and biophysical molecular processes in microbial organisms and host cells which lead to the initiation and progression of infectious diseases.

  3. Systems Biology Programs http://www3.niaid.nih.gov/research/resources/sb/ Established in September 2008

  4. “Omics” Programs Systems Biology Metabolomics Lipidomics Functional & Clinical Genomics Structural Genomics Centers Genomics Proteomics Sequencing Centers Pathogen Functional Genomics Center Structural Genomics Centers Clinical Proteomics Centers Systems Biology Centers Human Microbiome Project Bioinformatics Resource Centers http://www3.niaid.nih.gov/research/resources/dmid/data.htm

  5. Objectives of the meeting • Introduction to the Systems Biology Scientific Working Group (SBWG) • Introduction to each others to identify opportunities for collaborations • Identify common issues and solutions, related to pathogens’ biology, existing or promising new technologies

  6. NIAID Participants DMID • Irene Glowinski, DMID Deputy Director • Maria Giovanni, Chief, Genomics Group • Valentina Di Francesco, Genomics Group • Peter Dudley, Genomics Group • Malu Polanski, Genomics Group • Fred Cassels, SARS Program Officer • Bill Alexander, Salmonella Program Officer On the phone/web conferencing • Suman Mukhopadhyay, Yersinia Program Officer • Karen Lacourciere, TB Program Officer • Rachelle Salomon, Influenza Program Officer DAIT • Lynda Chiodetti, Section Chief, Basic Immunology Branch • Alison Yao, Program Officer

  7. Thank you University of Washington • Cynthia Baker • Lynn Law • Michael Katze DMID/Genomics Group • Peter Dudley Looking for a volunteer site for next year meeting

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