1 / 20

DNA

DNA. 1/22/09. The homonculus. The Different Parts of a Nucleotide. Nitrogenous Base. Phosphate. Sugar. Fig. 16-5. Nitrogenous bases. Sugar–phosphate backbone 5  end. Thymine (T). Adenine (A). Cytosine (C). DNA nucleotide. Phosphate.

ave
Download Presentation

DNA

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. DNA 1/22/09 The homonculus

  2. The Different Parts of a Nucleotide Nitrogenous Base Phosphate Sugar

  3. Fig. 16-5 Nitrogenous bases Sugar–phosphate backbone 5 end Thymine (T) Adenine (A) Cytosine (C) DNA nucleotide Phosphate Sugar (deoxyribose) 3 end Guanine (G)

  4. Percentage of Nitrogenous Bases in Four Organisms Source of DNA A T G C Streptococcus 29.8 31.6 20.5 18.0 Yeast 31.3 32.9 18.7 17.1 Herring 27.8 27.5 22.2 22.6 Human 30.9 29.4 19.9 19.8

  5. Fig. 16-6 (b) Franklin’s X-ray diffraction photograph of DNA (a) Rosalind Franklin

  6. Fig. 16-7a 5 end Hydrogen bond 3 end 1 nm 3.4 nm 3 end 0.34 nm 5 end (a) Key features of DNA structure (b) Partial chemical structure

  7. Fig. 16-8 Adenine (A) Thymine (T) Cytosine (C) Guanine (G)

  8. Fig. 16-12 Origin of replication Parental (template) strand Daughter (new) strand Replication fork Double- stranded DNA molecule Replication bubble 0.5 µm Two daughter DNA molecules (a) Origins of replication in E. coli Origin of replication Double-stranded DNA molecule Parental (template) strand Daughter (new) strand 0.25 µm Replication fork Bubble Two daughter DNA molecules (b) Origins of replication in eukaryotes

  9. Fig. 16-14 New strand 5 end Template strand 3 end 5 end 3 end Sugar T A A T Base Phosphate C G C G G C G C DNA polymerase 3 end A A T T 3 end Pyrophosphate C C Nucleoside triphosphate 5 end 5 end

  10. Fig. 16-15 Overview Origin of replication Leading strand Lagging strand Primer Lagging strand Leading strand Overall directions of replication Origin of replication 3 5 RNA primer 5 “Sliding clamp” 3 5 DNA poll III Parental DNA 3 5 5 3 5

  11. Fig. 16-16a Overview Origin of replication Leading strand Lagging strand Lagging strand 2 1 Leading strand Overall directions of replication

  12. Fig. 16-16b1 3 5 3 5 Template strand

  13. Fig. 16-16b2 3 5 3 5 Template strand 3 5 3 RNA primer 1 5

  14. Fig. 16-16b3 3 5 3 5 Template strand 3 5 3 RNA primer 1 5 3 Okazaki fragment 5 3 1 5

  15. Fig. 16-16b4 3 5 3 5 Template strand 3 5 3 RNA primer 1 5 3 Okazaki fragment 5 3 1 5 3 5 3 2 5 1

  16. Fig. 16-16b5 3 5 3 5 Template strand 3 5 3 RNA primer 1 5 3 Okazaki fragment 5 3 1 5 3 5 3 2 5 1 5 3 3 5 1 2

  17. Fig. 16-16b6 3 5 3 5 Template strand 3 5 3 RNA primer 1 5 3 Okazaki fragment 5 3 1 5 3 5 3 2 5 1 5 3 3 5 1 2 5 3 3 5 1 2 Overall direction of replication

  18. Fig. 16-18 Nucleotide Excision Repair Nuclease DNA polymerase DNA ligase

  19. Fig. 16-19 5 Ends of parental DNA strands Leading strand Lagging strand 3 The chromosome end replication problem Last fragment Previous fragment RNA primer Lagging strand 5 3 Parental strand Removal of primers and replacement with DNA where a 3 end is available 5 3 Second round of replication 5 New leading strand 3 5 New lagging strand 3 Further rounds of replication Shorter and shorter daughter molecules

  20. Telomerase

More Related