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Five Sense Biochemistry. Love thy Lipids. Lipid Chemistry. Main Elements of Lipids: Carbon hydrogen & oxygen The ratio of hydrogen to carbon is greater than 2:1. Lipid Chemistry. Lipids are non-polar, hydrophobic molecules
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Five Sense Biochemistry Love thy Lipids
Lipid Chemistry Main Elements of Lipids: Carbon hydrogen & oxygen The ratio of hydrogen to carbon is greater than 2:1
Lipid Chemistry • Lipids are non-polar, hydrophobic molecules • How do lipids behave in the presence of polar molecules such as water? • Lipids include fats, phospholipids, waxes & steroids
Function of Fats • Energy storage • Fats contain 9 calories/gram whereas carbohydrates contain 4 calories/gram
Fats • Fats are composed of glycerol & three fatty acids (tri-glyceride)
Saturated Fat • Study the pattern of carbon & hydrogen bonding—why do you think this is a saturated fat?
Unsaturated Fat • Study the pattern of carbon & hydrogen bonding—why do you think this is a unsaturated fat?
Unsaturated Fats: Structure & FunctionHow does the double bond affect the function of the molecule in cell membranes?
Trans Fats • Found in foods that contain partially hydrogenated oils • Linked to increased heart disease • Cause increased levels of “bad” blood cholesterol and decreased levels of “good” cholesterol • http://www.mayoclinic.com/health/trans-fat/CL00032 • http://www.indiana.edu/~oso/Fat/SolidNLiquid.html
Trans Fats • What makes trans fats different than other unsaturated fats? • How will this structure affect the molecule’s ability to bend?
Trans Fats & the Cell Membrane • Trans fats get stored in the cell membrane • As much as 20% of the cell membrane can consist of these unnatural fats • Trans fats don’t kink—how will this affect the function of the cell membrane?
Phospholipids • Similar to a fat, but contains only two fatty acids and a phosphate group. • Polar heads & non-polar tails • Where are phospholipids found in cells?
Steroids (Sterols) • Lipids with four fused rings & no fatty acids • Cholesterol is found in cell membranes & plays a role in hormone synthesis