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Nutrition. Sara R. Zwart, Ph.D. Nutritional Biochemistry Laboratory Johnson Space Center - NASA. Monica V. Trevathan Education Specialist Human Health and Performance Johnson Space Center - NASA. June 23, 2005. Learning Objectives.
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Sara R. Zwart, Ph.D. Nutritional Biochemistry Laboratory Johnson Space Center - NASA Monica V. Trevathan Education Specialist Human Health and Performance Johnson Space Center - NASA June 23, 2005
Learning Objectives Participants will expand their science content knowledge in the area of Nutrition by: • Describing the importance of proper nutrition for our bodies on Earth and for human space exploration. • Identifying human body systems that are affected by inadequate nutrition (on Earth and in space). • Explaining some challenges in nutrition and food for human exploration and long duration space flight.
Adaptation to Weightlessness • Muscle • Psychological/ Behavioral/ Performance • Bone • Fluid shifts, hematological • Taste & odor • Cardiovascular • Neurosensory • Gastrointestinal • Sleep &circadian rhythm • Environmental
What is the Function of Nutrition? • Psychosocial aspects • Meet energy/nutrient requirements • Countermeasure
Classroom Project Idea • Go to www.mypyramid.gov • My Pyramid Tracker can track food intake for 24 hours and give a report
In general, most astronauts eat less than their recommended intake. Does this necessarily mean they lose weight? Energy IntakePOLL QUESTION
Vitamin D • Stimulates calcium absorption in the intestine • Deficiency can lead to: • Rickets • Osteomalacia
POLL QUESTION Which of the following is NOT a source of Vitamin D?
Nutrients Critical for Bone Health • Calcium • Vitamin D • Vitamin K • Phosphorus • Magnesium
Bone Bone breakdown Bone formation
Bone Loss • Bone Loss • Fracture Risk • Stone Risk Adapted from Heaney et al, 2000
Potential Countermeasures • Nutrition • Exercise • Pharmacology
Biochemical Markers of Bone Breakdown • N-telopeptide • Helical peptide
Sodium NTX (nmol/d) Level of dietary sodium at each stage of the study Experiment days
Omega-3 Fatty Acids • Beneficial effects on cholesterol, lipid metabolism, and cardiovascular health • Inhibit muscle loss in subjects with hyper-catabolic diseases • Protective effects on bone health
Omega-3 Fatty Acids • Clinical trial with cancer cachexia patients (Wigmore et al. 1996)
Chicken Bone in Acid • In the classroom, use the “famous” chicken bone in acid lab experiment to demonstrate acid effects on bones • See: http://haco.jsc.nasa.gov/pdf/pH Experiment.pdf • ….plus, ideas for more on nutrition and bones!
Next Stop: Mars!! • Nutrition is critical due to length of missions • Critical issues: • Are vitamins stable after exposure to deep-space radiation? • Are nutrients stable for long shelf life (up to 5 years)?
Food System Issues • Nutrient content • Palatability • Shelf-life • Preparation • Storage • Trash
How will Extreme Conditions of Space Affect Food Supply? • Closed food system • Radiation • Long-term storage • Depletion of a single nutrient could be deadly after 3 years
For Example… Vitamin B1 (thiamine) • Easily destroyed by heat and light • Deficiency • beriberi • develops within 2-3 months • neurological and cardiovascular effects
Another Example Vitamin C • Deficiency • Scurvy • Bleeding around hair follicles, gums and underneath fingernails • Effects of radiation and long-duration storage are unknown for space flight
Nutrition Research On Earth and in space: • Nutrition is more than just eating food • Food choices are important • Nutrition affects all body systems • Countermeasures for conditions such as osteoporosis
Related NASA Education Material • National Space and Biomedical Research Institute • Activities Guides for Teachers • 5-8 grade http://www.nsbri.org/Education/index.html
Related NASA Education Material • NASA CONNECT™ • Math & Science integration • “Better Health from Space to Earth” • Grades 5-8 http://connect.larc.nasa.gov
Sara R. Zwart, Ph.D. Nutritional Biochemistry Laboratory Johnson Space Center - NASA Monica V. Trevathan Education Specialist Human Health and Performance Johnson Space Center - NASA