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Remote ischemic conditioning before primary PCI in STEMI patients

Remote ischemic conditioning before primary PCI in STEMI patients. Objective: To test the hypothesis that remote ischemic conditioning during STEMI before primary PCI increases myocardial salvage. Study: Single center, randomized trial.

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Remote ischemic conditioning before primary PCI in STEMI patients

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  1. Remote ischemic conditioning before primary PCI in STEMI patients Objective: To test the hypothesis that remote ischemic conditioning during STEMI before primary PCI increases myocardial salvage. Study: Single center, randomized trial. Population: Patients with first STEMI, < 12 hours of symptoms. Endpoint: Myocardial salvage index.

  2. Remote ischemic conditioning before primary PCI in STEMI patients Remote conditioning + Primary PCI n=166 700 MBq 99Tc- Sesta- mibi iv Perf. imaging 6 hours after Adm. Myo- cardium at risk repeat Perf. imaging at 30 days Final infarct size Compl imaging n=73 Enrolled n=333 Primary PCI n=167 Compl imaging n=69

  3. Remote ischemic conditioning before primary PCI in STEMI patients Scintigraphic results (median) (%) p=0.033 p=0.037 p=0.10

  4. Remote ischemic conditioning before primary PCI in STEMI patients Conclusion: Remote ischemic conditioning before hospital admission for primary PCI increases myocardial salvage. Bøtker et al. Lancet 2010;375:727-34

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