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Explicit length distribution models in Iscan

Explicit length distribution models in Iscan. Lab meeting 8/20/2003 By Chaochun Wei. Length distribution models in Iscan. Explicit length distribution models: Exon and intron. Effect of the intron length limit. Effect of the smoothlization of the length distribution models.

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Explicit length distribution models in Iscan

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  1. Explicit length distribution models in Iscan Lab meeting 8/20/2003 By Chaochun Wei

  2. Length distribution models in Iscan • Explicit length distribution models: • Exon and intron. • Effect of the intron length limit. • Effect of the smoothlization of the length distribution models.

  3. Effect of explicit intron length distribution on worm gene prediction • On WS82 single gene dataset (3255 genes), • 8-fold Cross validation

  4. Effect of the intron length Intr_len g_sn g_sp e_sn e_sp n_sn n_sp 1300 50.84% 28.31% 83.73% 64.58% 96.22% 77.30% 1600 51.89% 29.18% 84.47% 65.26% 96.43% 77.39% 1900 52.81% 29.93% 84.91% 65.77% 96.52% 77.52% 2200 53.00% 30.32% 85.23% 66.09% 96.60% 77.53% 2500 53.30% 30.62% 85.36% 66.31% 96.60% 77.59% 2800 53.58% 30.84% 85.47% 66.43% 96.61% 77.60% 3100 53.70% 30.94% 85.51% 66.48% 96.63% 77.61% 3700 53.95% 31.14% 85.60% 66.61% 96.64% 77.64% 4300 54.04% 31.23% 85.62% 66.67% 96.66% 77.66% 4900 54.10% 31.32% 85.63% 66.73% 96.66% 77.68% 5500 54.16% 31.41% 85.64% 66.78% 96.66% 77.69% 6100 54.19% 31.44% 85.64% 66.79% 96.65% 77.69% 6700 54.29% 31.51% 85.67% 66.83% 96.65% 77.69% 7000 54.32% 31.54% 85.69% 66.85% 96.66% 77.70%

  5. Effect of the Intron length

  6. Intron length distribution

  7. Effect of smoothlization of the length distribution 1. Not symmetric (original version) 2. Symmetric Gaussian

  8. Effect of smoothlization of the length distribution 1. Not symmetric (original version) 2. Symmetric Gaussian ( 8-fold cross validation result)

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