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HOW CAN I BE SURE THIS IS A STROKE ? DR. INDIRA NATARAJAN LOCUM CONSULTANT UNIVERSITY HOSPITAL OF NORTH STAFFRODSHIRE. WHO DEFINITION.
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HOW CAN I BE SURE THIS IS A STROKE ? • DR. INDIRA NATARAJAN LOCUM CONSULTANT UNIVERSITY HOSPITAL OF NORTH STAFFRODSHIRE
WHO DEFINITION “ rapidly developing clinical signs (at times global) disturbance of cerebral function, lasting more than 24 hours or leading to death with no apparent cause other than that of vascular origin” This definition includes signs and symptoms of suggestive of - ischaemic stroke - haemorrhages (intracerebral or subarachanoid)
IS THIS A STROKE? History - sudden onset of focal symptoms, risk factors for stroke, relevant past medical history Examination - neurological signs consistent with story
Diagnostic Dilemma • “ Stroke Mimics ” or “ Stroke Syndrome ” • 10% - 15% of patients referred with possible stroke have something else • Some uncertainty is inevitable
How to approach? • Focus on the event • Onset whether sudden or gradual • Try to get the sequence of events • Previously fit and well • Preceding illness • Similar episodes • Risk factors
Pattern Recognition • FACE • SPEECH • ARM • LEG
Stop and Think! • Drowsy and Delirious • Patient with headache • Drowsiness, confusion and headache
Drowsiness /Delirium • SEIZURES • METABOLIC / TOXIC • SUBDURAL HAEMATOMA
Seizures • Commonest cause of misdiagnosis • Eye witness • Look for Ictal features – loss of consciousness, convulsion, incontinence, tongue biting • Post Ictal features – sleepiness and confusion
METABOLIC • Hypoglycaemia • Alcohol and drugs • Hyponatraemia • Hypocalcaemia • Hepatic encephalopathy • Wernick-Korsakoff syndrome • Hyperglycaemia
Subdural Haematoma • Usually in the elderly • Recurrent fallers • If significant will cause drowsiness • Sometimes headache, confusion, hemiplegia or dysphasia • Features may fluctuate • Diagnosis : CT scan
Headache • VENOUS THROMBOSIS • MIGRAINE • CEREBRAL VASCULITIS • ARTERIAL DISSECTION
Venous Thrombosis • Most have headache • Half have raised ICP • Some have neurological signs • Prothrombotic state • D - Dimer • CSF if often abnormal – high protein and raised pressure • MR or CT venography diagnostic
Migraine • Visual aura • Visual phenomenon • Sensory symptoms • Dysphasia can occur • Headache
Cerebral Vasculitis • Unwell prior to the event • Look for clues • Results in infarcts or bleeds • ESR can be raised • MRI and CSF abnormal • Check auto antibodies
Arterial Dissection • History of Neck Trauma • Pain - Face and around eye • Unilateral Headache • Unilateral Neck pain – Carotid artery • Occipital pain – Vertebral artery • Ipsilateral Horner’s Syndrome • Ipsilateral Cranial nerve lesion and contralateral pyramidal tract lesion • CT MAY BE NORMAL – DISCUSS WITH RADIOLOGIST
HEADACHE AND DROWSINESS • CEREBRAL TUMOUR • ENCEPHALITIS • CEREBRAL ABSCESS
Cerebral Tumours • Onset is slower than stroke • Signs of Raised ICP – headache, vomiting, drowsiness, papilloedema • CT Scan confirms diagnosis • Sometimes further imaging needed
Encephalitis • Usually fit and well • Acute Confusional State • Mild preceding febrile illness, headache and drowsiness • Sometimes fits, and gradual onset coma • 15% of patients have focal signs • CT scan usually normal • CSF usually abnormal
Cerebral Abscess • Subacute onset • Usually spread from sinuses or ear • Headache usual • Signs of sepsis • Later drowsiness, vomiting, delirium • Dysphasia, visual field defects and facial weakness more common • Avoid LP • CT Scan
ALSO LOOK OUT FOR ATYPICAL CLINICAL PRESENTATIONS
Transient Global amnesia • Middle aged or elderly people • Sudden onset • Loss of memory for a period of time • No loss of personal identity • May have headache • Good recovery
Old Stroke with increased weakness • Old neurological signs often worse during intercurrent illness • Rapid return to previous level of function is usual with appropriate treatment
Syncopal episodes • Loss of consciousness • Light headedness with diminishing loss of vision
Hysteria / Functional • Young patient • Focal neurology not fitting with examination • Similar events in the past • Mental health issues • Hyperventilation
FACIAL PALSY • Bell’s Palsy • Low NIHSS score
To Summarise….. • Sudden onset • Risk factors for vascular event • Clear pattern of weakness It is a Stroke
Features prompting caution…. • Atypical pattern of weakness • Drowsy/ Delirium • Headache • Pyrexia • Malaise or prodromal illness • Gradual progression over days • Features of raised ICP • Young age or absence of risk factors