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The Anterior Pituitary Gland:

The Anterior Pituitary Gland:. By Krista & Mandy. Location. it weighs about >0.5g 1 of 2 functionally distinct parts makes up 75% of the total weight of the pituitary also known as: adenohypophysis. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/structur.htm.

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The Anterior Pituitary Gland:

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  1. The Anterior Pituitary Gland: By Krista & Mandy

  2. Location it weighs about >0.5g 1 of 2 functionally distinct parts makes up 75% of the total weight of the pituitary also known as: adenohypophysis http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/structur.htm

  3. Hormones Produced There are 6 major hormones: Thyroid Stimulating Hormone (TSH) Follicle Stimulating Hormone (FSH) Luteinizing Hormone (LH) Growth Hormone (GH) Prolactin Hormone (PRL) Adrenocorticotrophic Hormone (ACTH)

  4. Thyroid Stimulating Hormone Target: Thyroid causes synthesis and secretion of triiodothyronine and thyroxine by the thyroid gland factors that affect the release of TRH from hypothalamus: blood levels, glucose and the body’s metabolic rate Deficiency: Metabolism, Cardiovascular, GT tract, and Motor Nervous System What can go wrong? - congenital problems affecting any of the pituitary hormones, loss of midline structures like septo-optic dysplasia causing loss of the optic nerve.

  5. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/tsh.htmhttp://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/tsh.htm

  6. Luteinizing Hormone & Follicle Stimulating Hormone Target: Ovaries in females & testes in males Induces ovulation in females & stimulates secretion of oestradiol and progesterone in females Acts on Leydig cells of testes to produce testosterone in males & maintains spermatogenesis, the production of sex hormone binding globulin Deficiency: Irregular menstrual cycle, affected production of sperm, infertility or impotence What can go wrong? amenorrhoea, creating a lack of ovulation in females and infertility in men, failure of gondal function

  7. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/FSH%26LH.htmhttp://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/FSH%26LH.htm

  8. Growth Hormone Target: All cells in the body controls 2 hypothalmic hormones  2 types of IGP’s, IGP 1 & IGP 2 factors that affect GHRH are stress, sleeping,exercise and blood glucose levels Deficiency: under development of bone, soft tissue,viscera and the metabolism, weakness What can go wrong? Gigantism, acromegaly, insulin resistance, GH secreting tumors

  9. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/gh.htmhttp://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/gh.htm

  10. Prolactin Hormone Target: Breasts Initiates and maintains milk secretion by the mammary glands May play a part in fertility and maternal behaviour Deficiency: little or no production of breast milk, problems with fertility What can go wrong? High levels can lead to loss of reproductive function and inappropriate milk production

  11. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/prl.htmhttp://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/prl.htm

  12. Adrenocorticotrophic Hormone Target: Adrenals Controls the production of glucocorticoids by adrenal cortex, stimulating conversion of cholesterol to pregnenolone - a precursor of cortisol ACTH - released from pituitary following a circadian rhythm - peaking in the morning then declines Deficiency: stressed out What can go wrong? Cushing Syndrome  body tissue exposed to cortisol for long periods of time

  13. http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/ACTH.htmhttp://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/ACTH.htm

  14. Effects of Hormones on the Anterior Pituitary http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/function.htm

  15. Complications changes in weight (gain or loss) swollen or enlarged body parts blood pressure problems personality changes skin changes temperature sensitivity weakness irregular menstruation cycle infertility/ impotence

  16. Works Cited Farr, Dr. Gary. "The Pituitary Gland." Become Healthy Now. 10 June 2002. 05 June 2009 <http://www.becomehealthynow.com/article/bodyendocrine/734/>. "Pituitary Tumor." Health News - The New York Times. 18 Mar. 2008. 05 June 2009 <http://health.nytimes.com/health/guides/disease/pituitary- tumor/overview.html>. "Site Map." Faculty of Life Sciences ELP: e-Learning Projects. 06 June 2009 <http://www.elp.manchester.ac.uk/pub_projects/2000/mnby6kas/sit emap.htm>.

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