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Linkage and Gene Maps. T. H. Morgan Lexington Native UK Alumni Nobel Prize Winne. Thomas Hunt Morgan. Lexingtonian Thomas Hunt Morgan worked on the fruit fly, Drosophila melanogaster . Morgan showed that Mendel’s principles applied to animals and not just pea plants.
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Linkage and Gene Maps T. H. Morgan Lexington Native UK Alumni Nobel Prize Winne
Thomas Hunt Morgan • Lexingtonian Thomas Hunt Morgan worked on the fruit fly, Drosophila melanogaster. • Morgan showed that Mendel’s principles applied to animals and not just pea plants. • He was the first Kentuckian (and only… for now) to be awarded the Nobel Prize in Medicine. • He was awarded this for determining that some traits were sex-linked and found on sex chromosomes. We’ll discuss this more later
T. H. Morgan • He also discovered the principle of linkage. • He discovered that each chromosomes is a set of linked genes. • He found that chromosomes assort independently, not individual genes.
Crossing Over and Gene Maps • Crossing over occasionally separates linked genes and produces new combinations of alleles. • This is important for genetic diversity.
Alfred Sturtevant • Alfred Sturtevant, a student in Morgan’s lab found that the further two genes are apart, the less likely they are to be inherited together.
Gene Maps • Sturtevant created a gene map, which shows the relative location of genes on a chromosome. • The map units are now called centimorgans (cM) in honor of T. H. Morgan
Crossing Over, Mutations, and Genetic Diversity • Very rare genetic mutation, a yellow Northern Carindal