1 / 21

SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987)

SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987). SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987). RETROSYNTHESIS OF AMPHOTERICIN B ACCORDING TO K. C. NICOLAOU. RETROSYNTHESIS OF AMPHOTERICIN B. Threedifferent types of –OH protection. Trans double bond formation.

bo-reeves
Download Presentation

SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987)

  2. SYNTHESIS OF AMPHOTERICIN B (K. C. NICOLAOU 1987)

  3. RETROSYNTHESIS OF AMPHOTERICIN B ACCORDING TO K. C. NICOLAOU

  4. RETROSYNTHESIS OF AMPHOTERICIN B Threedifferent types of –OH protection Trans double bond formation

  5. THE HORNER-WADSWORTH-EMMONS OLEFINATION(Ketophosphonate-aldehyde condensation) JACS, 1961, 83, 1733-1738

  6. RETROSYNTHESIS OF AMPHOTERICIN B

  7. RETROSYNTHESIS OF AMPHOTERICIN B These carbons are temporarily kept as protected alcohols

  8. RETROSYNTHESIS OF AMPHOTERICIN B

  9. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

  10. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

  11. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

  12. THE BARTON-McCOMBIE REACTION MECHANISM

  13. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

  14. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

  15. SYNTHESIS OF NORTH-EASTERN SECTION OF AMPHOTERICIN B

More Related