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Roles of the nephron. Some Fun Facts !!!. 120 ml of blood filtered by the kidney each minute! Only 1 ml of the 120 ml actually made into urine Your bladder can collect from 300 to 400 ml of urine before you have to take a *tinkle*
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Some Fun Facts !!! • 120 ml of blood filtered by the kidney each minute! • Only 1 ml of the 120 ml actually made into urine • Your bladder can collect from 300 to 400 ml of urine before you have to take a *tinkle* • 119 ml of filtered fluid (called FILTRATE) is moved back into the blood
If that didn’t happen…. • You’d have to pee once every 3 minutes • And drink 1 L of fluids every 10 minutes to maintain Homeostasis!
The Kidneys are therefore… • Very efficient at returning stuff back to the blood when needed • And removing wastes as needed
Urine Production by Kidneys • This happens in 3 main steps: • Filtration • Reabsorption • Secretion
Filtration • Blood enters glomerulus under high pressure • Pressure causes 20% of blood plasma (120 ml of 600 ml) to be forced into the Bowman’s Capsule • Water, salt, glucose, amino acids and urea (good stuff and bad stuffall pass through into BC • Blood Cells and proteins don’t enter the BC – too large to exit the capillaries • Filtrate – ISOTONIC to PLASMA
Reabsorption • The “wanted” stuff or “good stuff” that filters into the nephron is then reabsorbed back to the blood • Good stuff includes salts, glucose, amino acids • Reabsorption takes place in the regions of the Proximal and Distal Convoluted Tubules.
Secretion • Non useful wastes and toxins are ACTIVELY TRANSPORTED from the blood into the nephron • This “BAD STUFF” is “fast tracked” into the PCT, DCT, and CTof the nephron • Things like extra H+ ions, extra OH-, extra glucose, ammonia, drugs,
Secretion chart • Read the paragraph on Secretion and fill in the chart
Reabsorption chart • Read through the reabsorption section to fill in the chart • This is due MONDAY – April 26
Plasma Filtrate Urine Urine, modified filtrate, in collecting tubule Plasma, in blood vessels Filtrate, filtered plasma, in nephron
Venn diagramPlasma Filtrate Urine Plasma Filtrate Urine